ID A0A3Q1KHZ7_ANATE Unreviewed; 706 AA.
AC A0A3Q1KHZ7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Mitofusin 2 {ECO:0000313|Ensembl:ENSATEP00000036136.1};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000036136.1, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000036136.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004374}.
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DR AlphaFoldDB; A0A3Q1KHZ7; -.
DR Ensembl; ENSATET00000036653.2; ENSATEP00000036136.1; ENSATEG00000024839.2.
DR GeneTree; ENSGT00390000013727; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0008053; P:mitochondrial fusion; IEA:InterPro.
DR CDD; cd09912; DLP_2; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR006884; Fzo/mitofusin_HR2.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027094; Mitofusin_fam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10465:SF1; MITOFUSIN-2; 1.
DR PANTHER; PTHR10465; TRANSMEMBRANE GTPASE FZO1; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF04799; Fzo_mitofusin; 1.
DR SUPFAM; SSF111479; Fzo-like conserved region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 578..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..343
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT COILED 649..686
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 706 AA; 80642 MW; 1CBFBC511C61300F CRC64;
MSLVFPRPNT NTVHGKKDKR LMAEVNASPL KHFVTAKKKI NGIFEQLGAY IKESASFLED
THKNEELDPV TTEEQVQEVR GYLTKVASIG EVLARRQMKV VFFGRTSNGK SSVINAMLCD
KVLPSGIGHT TNCFLRVEGT DGNEAFLLTE GSEERKSIKT VNHLAHALHQ DEDLDAGSLV
CVMWPKAKCA LLRDDLVLVD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKS
FFHKVNERLS SPNIFILNNR WDASASEPEY MDEVHRQHMD RCTNFLVDEL GVVDRAQASD
RIFFVSAKEV LQARVQKAQG MPEAGGALAE GFQARMFEFQ NFERRFEECI SQSAVKTKFE
QHTVRAKQIS EALRCIMDSV HIAAQEQRIY CLETKEDRQD RLEFIDNQLD LLTMDCKAKI
KKITEEVEKQ VSNAFAEEIR KLHVLVDDFH MDFHPSLVVL KVYKNELHRH IEEGLGKNMS
ERCSTSITSA LQATQTIMIE GLKPLLPIPV REQVDKLVPR QCFSLSYDLA CDKLCSDFQE
DISFHFSLGW TMLVNRFLGP KNTRRALIGY NNQIWKAVGW RLIALSVGLY GLLYIYERLT
WTTKAKERTF KRQFVDYATE KLQLIVSYTG SNCSHQVQQE LAGVFAQLCQ QVDVTRQNLE
DEITDMNRKI ELLNSLQSKA KLLRNKAGWL DSELNMFTQQ YLHHSK
//
