ID A0A3Q1KI98_ANATE Unreviewed; 1037 AA.
AC A0A3Q1KI98;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSATEP00000036381.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000036381.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000036381.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU003762}.
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DR AlphaFoldDB; A0A3Q1KI98; -.
DR STRING; 64144.ENSATEP00000036381; -.
DR Ensembl; ENSATET00000036901.2; ENSATEP00000036381.2; ENSATEG00000024998.2.
DR GeneTree; ENSGT00940000159891; -.
DR Proteomes; UP000265040; Unplaced.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF90; INTEGRIN ALPHA-7; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR PROSITE; PS51470; FG_GAP; 5.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 34..1037
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5030001859"
FT TRANSMEM 569..588
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT TRANSMEM 739..761
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT TRANSMEM 960..985
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 37..103
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 183..236
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 300..361
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 362..418
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 422..481
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 466..564
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 600..720
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT DOMAIN 773..938
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
SQ SEQUENCE 1037 AA; 116182 MW; 3A6C77FB1608F931 CRC64;
MGHGNTVSHS PCSPHCWTTL LWVLLTLLGQ VWAFNLDTTH TLHKLGDRGT FFGFSLALHQ
QLTPEPQSWI LVGAPQAAGQ GLLRGSRPGA LFRCPITPEE YDCERVDIDG EGEFESKDNQ
WLGVTVKSQG IGGKVVTCAH LYELRQRVSQ TSETRDPIGR CYVLSEDLTE RDDLDGGEWK
FCEGRPQGHE QFGFCQQGLS VSFTPDNNFI LFGAPGTYNW KGLLFMASPV EDALLYKTLE
PSRRPTPFED VAHNSYLGFS VDSAMGIMSL GELTFVAGAP RANHTGAVVL LKKDNVYRLV
PQHIFWGEEL ASSFGYSVAT TDLNKDGWTD LIVGAPNFFD RKAEIGGAVY VYLNPFGHWD
DQARPIRLNG TYDSMFGMTV SNIGDVDQDG YGDIAVGAPF DGDGKVFIYR GSDAGIETKP
AQVLDGRDFD VKRFGYSISG GLDIDKNHYP DVAVGSLNDS VVLFRSRPVI HVIREISIDP
QNIDLEQQNC KGRDGCSLSL LLFFTPFQVL AVHFEADTER RKLGLPHRVN FLGRSSLEPE
YTQTEEVELH RQRHPACTTA VFQLHVSDLY FQFYSPFFFQ FLVMMFLVSS LKVNFLREGC
GSDKICQSNL QLSYQFGTRP LTSDLFTPLP IDEDGVQVFS LSDQRLVVLE ITVTNMPSDP
LHPEEDGDDA HAAQLNISLP DTLSYAGSRI PPQMRCQANQ NGSQVECDLG NPVKRDTKVR
KQNQQNFYIS SGRRHKRNVL HVVLDFYYLF QILCVCLYMY LSDTLIPHFC RLARPHQLFF
SGTVKGESAM TSLEDVGSPV DFEFVVANPG KVLQTLGSAF LNIMWPYELA NEKWLLYPAS
LTFEGHPDTQ CTPTGALNPL KLESSSSAEQ PVNHKDCLLG SARCVVFQCP LHSFSGQAVL
KIHARLWNSS FIEDFSAVSA LELLVRANIT VKSSIRHLLL KDAAVPVMIY PEHGLADQYW
IPWWIILIAI LAGILLLTLL VCILWKCGFF RRAHYKDKLP QYHAVKIPRE DRPQFQTEKS
GVVHKKEWAT HWSDGTL
//
