ID A0A3Q1LQF4_BOVIN Unreviewed; 443 AA.
AC A0A3Q1LQF4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Tubby-like protein {ECO:0000256|RuleBase:RU361125};
GN Name=TULP3 {ECO:0000313|Ensembl:ENSBTAP00000057194.1,
GN ECO:0000313|VGNC:VGNC:36521};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000057194.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000057194.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000057194.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000057194.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000057194.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000256|ARBA:ARBA00007129,
CC ECO:0000256|RuleBase:RU361125}.
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DR AlphaFoldDB; A0A3Q1LQF4; -.
DR Ensembl; ENSBTAT00000075558.1; ENSBTAP00000057194.1; ENSBTAG00000015879.6.
DR VEuPathDB; HostDB:ENSBTAG00000015879; -.
DR VGNC; VGNC:36521; TULP3.
DR GeneTree; ENSGT00940000158155; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000015879; Expressed in olfactory segment of nasal mucosa and 104 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1LQF4; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR InterPro; IPR005398; Tubby_N.
DR PANTHER; PTHR16517; TUBBY-RELATED; 1.
DR PANTHER; PTHR16517:SF138; TUBBY-RELATED PROTEIN 3; 1.
DR Pfam; PF01167; Tub; 1.
DR Pfam; PF16322; Tub_N; 2.
DR PRINTS; PR01573; SUPERTUBBY.
DR PRINTS; PR01574; TUBBYPROTEIN.
DR SUPFAM; SSF54518; Tubby C-terminal domain-like; 1.
DR PROSITE; PS01200; TUB_1; 1.
DR PROSITE; PS01201; TUB_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 10..58
FT /note="Tubby N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16322"
FT DOMAIN 64..174
FT /note="Tubby N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16322"
FT DOMAIN 195..438
FT /note="Tubby C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01167"
FT REGION 93..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 49218 MW; 1FF4FE277B298D7F CRC64;
MKLRQLKLDN QRALLEKKQR KKRLEPLMVQ PNLEARPLRA RPRGREEHAL LVEPQAPQGG
VILQGIDGPA AFLKPDAQDV DTRLHVLTVG SAATEDAEGS ADGESARDPA SKPDLQEVLR
KHGISGSLNF DEEETDGEEG EGNQLRSQSP CSEAERPGSA SSQKPAPGTG ASGTASPHSD
IQPGEIEDLE GFAYSPAPRG VTVKCRITRD KKGMDRGLFP TYYMHLEKDE NRKIFLLAGR
KRKKSKTSNY LISTDPTDLS REGESYIGKL RSNLMGTKFT VYDHGVSPAK AQGLVEKAYT
RQELAAVCYE TNVLGFKGPR KMSVIIPGMN MNHERIPFQP RNDHESLLSK WQNKAMENLI
ELHNKSPVWN DDTQSYVLNF HGRVTQASVK NFQIVHDNDP DYIVMQFGRV ADDVFTLDYN
YPLCALQAFA IGLSSFDSKL ACE
//
