ID A0A3Q1LTQ2_BOVIN Unreviewed; 1076 AA.
AC A0A3Q1LTQ2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ELKS/RAB6-interacting/CAST family member 1 {ECO:0000313|Ensembl:ENSBTAP00000060727.1};
GN Name=ERC1 {ECO:0000313|Ensembl:ENSBTAP00000060727.1,
GN ECO:0000313|VGNC:VGNC:28566};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000060727.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000060727.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000060727.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000060727.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000060727.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_010803958.1; XM_010805656.2.
DR AlphaFoldDB; A0A3Q1LTQ2; -.
DR Ensembl; ENSBTAT00000079957.1; ENSBTAP00000060727.1; ENSBTAG00000013658.7.
DR GeneID; 519271; -.
DR CTD; 23085; -.
DR VEuPathDB; HostDB:ENSBTAG00000013658; -.
DR VGNC; VGNC:28566; ERC1.
DR GeneTree; ENSGT00650000093320; -.
DR OrthoDB; 2880381at2759; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000013658; Expressed in granulosa cell and 109 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1LTQ2; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0098793; C:presynapse; IEA:UniProt.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.2440; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR019323; ELKS/CAST.
DR InterPro; IPR037245; FIP-RBD_C_sf.
DR InterPro; IPR019018; Rab-bd_FIP-RBD.
DR PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR Pfam; PF10174; Cast; 2.
DR Pfam; PF09457; RBD-FIP; 1.
DR SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS51511; FIP_RBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 1006..1068
FT /note="FIP-RBD"
FT /evidence="ECO:0000259|PROSITE:PS51511"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 151..178
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 215..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1017..1047
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 31..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..826
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1076 AA; 123067 MW; 67FF36E4F8B0CA89 CRC64;
MYGSARSVGK VEPSTQSPGR SPRLPRSPRL GHRRTNSTGG SSGSSAGGGG GKTLSMENIQ
SLNAAYATSG PMYLSDHENA GSETPKSTMT LGRSGGRLPY GVRMTAMGSS PNIASSGVAS
DTIAFGEHHL PPVSMASTVP HSLRQARDNT IMDLQTQLKE VLRENDLLRK DVEVKESKLS
SSMNSIKTFW SPELKKERAL RKDEASKITV WKEQYRVVQE ENQHMQMTIQ ALQDELRIQR
DLNQLFQQDS SSRTGEPCVA ELTEENFQRL HAEHERQAKE LFLLRKTLEE MELRIETQKQ
TLNARDESIK KLLEMLQSKG LSAKATEEDH ERTRRLAEAE MHVHHLESLL EQKEKENALL
REEMHRRFEN APDSAKTKAL QTVIEMKDSK ISSMERGLRD LEEEIQMLKS NGALSTEERE
EEMKQMEVYR SHSKFMKNKV EQLKEELSSK EAQGEELKKR AAGLQAEIGQ VKQELSRKDT
ELLALQTKLE TLTNQFSDSK QHIEVLKESL TAKEQRAAIL QTEVDALRLR LEEKETMLNK
KTKQIQDMAE EKGTQAGEIH DLKDMLDVKE RKVNVLQKKI ENLQEQLRDK EKQMSSLKER
VKSLQADTTN TDTALTTLEE ALAEKERTIE RLKEQRDRDE REKQEEIDNY KKDLKDLKEK
VSVLQGDLSE KEASLLDLKE HASSLASSGL KKDSRLKTLE IALEQKKEEC LKMESQLKKA
HEATLEARAS PEMSDRIQQL EREIARYKDE SSKAQAEVDR LLEILKEVEN EKNDKDKKIA
ELESLTSRQV KDQNKKVASL KHKEQVEKKK SAQMLEEARR REDTLSDSSQ QLQVEELLMA
MEKVKQELES MKAKLSSTQQ SLAEKETHLT NLRAERRKHL EEVLEMKQEA LLAAISEKDA
NIALLELSSS KKKTQEEVAA LKREKDRLVQ QLKQQTQNRM KLMADNYEDD HFRSSHSGQS
NHKPSPDQII QSLLELDQNR SKLKLYIRHL TALCHDRDPL ILRGLTPPAA YKLDDDQAAW
ENELQKMTQE QLQSEQEKGE RDNAELQEFA NAVLQQIADH CPDILEQVVN ALEESS
//
