ID A0A3Q1LUL1_BOVIN Unreviewed; 1791 AA.
AC A0A3Q1LUL1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Anaphase promoting complex subunit 1 {ECO:0000313|Ensembl:ENSBTAP00000064233.1};
GN Name=ANAPC1 {ECO:0000313|Ensembl:ENSBTAP00000064233.1,
GN ECO:0000313|VGNC:VGNC:25879};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000064233.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000064233.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000064233.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000064233.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000064233.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
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DR Ensembl; ENSBTAT00000069141.1; ENSBTAP00000064233.1; ENSBTAG00000027991.5.
DR VEuPathDB; HostDB:ENSBTAG00000027991; -.
DR VGNC; VGNC:25879; ANAPC1.
DR GeneTree; ENSGT00390000016757; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000027991; Expressed in spermatocyte and 108 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1LUL1; baseline and differential.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 1.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 81..199
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 615..927
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1524..1609
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1643..1769
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
FT REGION 315..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1791 AA; 200187 MW; AE29DE6AF00323D6 CRC64;
MSNFYEERAT MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS
LQEVTIHEKQ KESWQLRKGV SEIGEEVDYD EELYMAGNMV IWSKGSKSQA LAVYKAFTVD
SPVQQALWCD FIISQDKSDK DYMERCICIL QSSCINMHSI EGKDYIASLP FQVANVWPTK
YGLLFERSSS SCEVPPGPPR EPLPTLFSML HPLDEITPVV CKSGSLFGSS RVQYVVDHAM
KIVFLHTDPS IVMTYDTVQG LHSVWALRRV KTEEGNVVLK FSEQGGTPQN VATSSSLTAH
LRSLSKGDSP VASPFQNYSS IHSQSRSASS PSLHSRSPSI SNMAALSRAH SPALGVYSFS
GVQRFNLSSH NQSPKRHSFS HSPSSNSNGS FLAPETEPIV PELCIDHLWT ETITRLRKKN
SQASKVFITS DLCGQKFLCY LVESELQLRC VKFQESNDKT QLIFGSVTNI QAKDAAPVEV
NNGVKSLCII VKPYAKKTCN FFIQISQKCF TCCIYDPVQV LVSPVPELRD SSKLHDSLYT
EDCTFQQLGT YIHSIRDPVR NRVTLVIQTC LQAIKFILPK EIAVQMLVKW YSVHSAPGGP
SDHSEWNLFV TCLMNMMGYN TDRLAWTRNF DFEGSLSPVI APKKARPSET GSDDDWEYLL
NSDYHQNVES HLLNRSLCLS PLEVSQMKDE DFSQNLSLDS STLLFTHIPA IFFVLHLVYE
ELKLNTLMGE GVRSLVELLV QLARDLKLEP YIDHYYRDYP TLVRTTGQVC AIDQGQTGSM
QYPPFFTPEP PSIYQWVSSC LKGEGVPPYP YLPGICERGR LVVLSIALYI LGDESSLSDE
SSQYLSRISI GKSSLLTLFG GLGQWLSLTE EFSPFPPSQG FTLRDLETLP FGIALPIRDA
IYHCREQPAS DWPEAVCLLI GRQDLSKQAC EGNLPKGKSV NVPSGTETEE EDDGMNDMNQ
EVMSLIWSED LRVQDVRRLL QSAHPVRVNV VQYPELSDHE FIEEKENRLL QLCQRTMALP
VGRGMFTLFS YHPVPTEPLP IPKLNLTGRA PPRNTTVDLN SGNIDVPPNM TSWASFHNGV
AAGLKIAPAS QIDSAWIVYN KPKHAELANE YAGFLMALGL NGHLTKLATL NIHDYLTKGH
EMTSIGLLLG VAAAKLGTMD MSVTRLLSIH IPALLPPTST ELDVPHNVQV AAVVGIGLVY
QGTAHRHTAE VLLAEIGRPP GPEMEYCTDR ESYSLAAGLA LGMVCLGHGS NLIGMSDLNV
PEQLYQYMVG GHRRFQAGMH REKHKSPSYQ IKEGDTINVD VTCPGATLAL AMIYLKTNNS
VTAWPIADWL RAPDTMYLLD FVKPEFLLLR TLARCLILWD DILPNSKWVD SNVPQIIREN
SISLSEIELP CSEDLNLETL SQAHVYIIAG ACLSLGFRFA GSENLSAFNC LTGPYNLETC
LSVVLLSLAM VMAGSGNLKV LQLCRFLHMK TGGEMNYGFH LSHHRPLGLP LLCCLPLSRP
FVFSVNRYHL QALRHLYVLA AEPRLLVPVD VDTNMPCYAL LEVTYKGTQW YEQTKEELMA
PTLLPELHLL KQIKVKGPRY WELLIDLSKG TQHLKSILSK DGVLYVKLRA GQLSYKEDPM
GWQSLLAQTV ANRNSEARAF KPETISTFTS DPALLSFAEY FCKPTVNKQE LLDLFSSVLY
ECVTQETPEM LPAYIAMDQA VRRLGRREMS ETSDLWQIKL VLEFFSSRSH QERLQNQPNR
GLFMNSEFLP VVKCTTDNTL DQWLQGESST APLSFELHWV SGLSVFTCFP W
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