ID   A0A3Q1LZA3_BOVIN        Unreviewed;       432 AA.
AC   A0A3Q1LZA3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=UEV and lactate/malate dehyrogenase domains {ECO:0000313|Ensembl:ENSBTAP00000061026.1};
GN   Name=UEVLD {ECO:0000313|Ensembl:ENSBTAP00000061026.1,
GN   ECO:0000313|VGNC:VGNC:36643};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000061026.1, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000061026.1, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000061026.1,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000061026.1}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000061026.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_015316652.1; XM_015461166.1.
DR   Ensembl; ENSBTAT00000080025.1; ENSBTAP00000061026.1; ENSBTAG00000013568.5.
DR   Ensembl; ENSBTAT00000083442.1; ENSBTAP00000068098.1; ENSBTAG00000013568.5.
DR   VEuPathDB; HostDB:ENSBTAG00000013568; -.
DR   VGNC; VGNC:36643; UEVLD.
DR   GeneTree; ENSGT00940000153903; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000013568; Expressed in spermatid and 107 other cell types or tissues.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   CDD; cd05293; LDH_1; 1.
DR   Gene3D; 3.90.110.10; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR001557; L-lactate/malate_DH.
DR   InterPro; IPR022383; Lactate/malate_DH_C.
DR   InterPro; IPR001236; Lactate/malate_DH_N.
DR   InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR008883; UEV_N.
DR   PANTHER; PTHR43128; L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)); 1.
DR   PANTHER; PTHR43128:SF32; UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3; 1.
DR   Pfam; PF02866; Ldh_1_C; 1.
DR   Pfam; PF00056; Ldh_1_N; 1.
DR   Pfam; PF05743; UEV; 1.
DR   PRINTS; PR00086; LLDHDRGNASE.
DR   SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS51322; UEV; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          1..106
FT                   /note="UEV"
FT                   /evidence="ECO:0000259|PROSITE:PS51322"
SQ   SEQUENCE   432 AA;  47375 MW;  461CED7D0D3DCB5E CRC64;
     MVQVFKDSSQ KDLLNFTGTI PVIYQGNTYN IPIRLWILDS HPFAPPICFL KPTANMGILV
     GKHVDAQGRI YLPYLQNWSH PKSVIVGLIK EMIAKFQDEL PLCSLSSSDE ARQVDLLAYI
     AKITEGVSDI NSKNWANREN KTVNKITVVG GGELGIACTL AISAKGIADK LVLLDFSEGT
     KGGMMDLDIF NLPNVEISKD LSASAHSKVV IFTVNSLGSS QSYLDVVQSN VDMFRALVPA
     LGHYSQHAIL LVASQPVEIM TYVTWKLSAF PANRVIGIGC NLDSQRLQYI ITNVLKAQTS
     GKEVWVIGEQ GEDKVPIWSG QEEVTNHDSQ MQLSNRAMEL LRVKGQRSWS VGLSVADLLD
     SIVNDKKKVH SVSILAKGYY DINSEVFLSL PCILGTSGVS EVIKTTVKEE TVTEKLQSSA
     SSIHGLQQQL KL
//