ID   A0A3Q1M3R4_BOVIN        Unreviewed;       451 AA.
AC   A0A3Q1M3R4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000068172.1, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000068172.1, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000068172.1,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000068172.1}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000068172.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the beta type-B retroviral polymerase family.
CC       HERV class-II K(HML-2) pol subfamily. {ECO:0000256|ARBA:ARBA00010879}.
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DR   AlphaFoldDB; A0A3Q1M3R4; -.
DR   Ensembl; ENSBTAT00000080497.1; ENSBTAP00000068172.1; ENSBTAG00000048394.1.
DR   VEuPathDB; HostDB:ENSBTAG00000048394; -.
DR   GeneTree; ENSGT01100000263481; -.
DR   InParanoid; A0A3Q1M3R4; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000048394; Expressed in monocyte and 36 other cell types or tissues.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR47027; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47027:SF8; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; ERV {ECO:0000256|ARBA:ARBA00022783};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          32..300
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   COILED          213..259
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   451 AA;  52061 MW;  36327F7BC1B8C6D8 CRC64;
     MNKASASDGI PVELFQILED DAVKVLHSIR QQVWKTQQWT QDWKRSVFIP IPKKGNDKEC
     SNYRTIALIS HASKVMLKIL QARLQQYVNR ELPDVQAGFR KGRETRDQIA NILWIIEKAR
     EFQKNIYFCF IDYAKAFDCV DHNKLWKILK EMGIPDHLTC LLRNLYAGQE ATVRTGLGTT
     DWFQIGKGVR QGCILSPCLF NFQAEYIMRN AGLEEAQAGI KIARRNINNL RYADDTTLVA
     ESEEELKSLL MKVKEESKKV GLKLNIQKTK IMASGLITSW EIDGETVETV SDFIFLGSKI
     TADGDCSLEI KRCLLLRRRV MTNLDSIFKS RDVTWPTKVC LVKAMVFPVV MYGCESWTVK
     KAECQRIDAF ELWCWRRLLR VPWTARRSNQ SILKEISPGC SLEGLMLKLQ LQYFGHLMRR
     VDSLEKTLML GGFGGRRRGQ RRMRWLDGIT D
//