ID A0A3Q1M3S5_BOVIN Unreviewed; 409 AA.
AC A0A3Q1M3S5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
GN Name=LRRFIP2 {ECO:0000313|Ensembl:ENSBTAP00000064423.1,
GN ECO:0000313|VGNC:VGNC:31035};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000064423.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000064423.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000064423.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000064423.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000064423.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
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DR AlphaFoldDB; A0A3Q1M3S5; -.
DR Ensembl; ENSBTAT00000084010.1; ENSBTAP00000064423.1; ENSBTAG00000016760.6.
DR VEuPathDB; HostDB:ENSBTAG00000016760; -.
DR VGNC; VGNC:31035; LRRFIP2.
DR GeneTree; ENSGT00530000063564; -.
DR Proteomes; UP000009136; Chromosome 22.
DR Bgee; ENSBTAG00000016760; Expressed in cardiac atrium and 107 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1M3S5; baseline and differential.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR Pfam; PF09738; LRRFIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 118..211
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 258..285
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 311..401
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 46777 MW; 829F454F0665D214 CRC64;
MRELERQQKE EESERARSSH RSSHRRPSLG VEDALSIRSL GSHRLDEKSD KQYAENYTRP
SSRNSASATT PLSGNSSRRG SGDTSSLIDP DTSLSELRDI YDLKDQIQDV EGRYMQGLKE
LKESLSEVEE KYKKAMVSNA QLDNEKNNLI YQVDTLKDVI EEQEEQMAEF YRENEEKSKE
LERQKHMCSV LQHKMDELKE GLRQRDELIE KHGLVIIPDG TPNGDVHQEP AVGAITVVSQ
EAAQVLESAG EGPLDVRLRK LAGEKEELLS QIRKLKLQLE EERQKCSGRD GTAGDLAELQ
NGSDLQLIEM QRDANRQISE YKFKLSKAEQ DITTLEQSIS RLEGQVLRYR TAAENAEKVE
DELKAEKRKL QRELRTALDK IEEMEMTNSH LAKRLEKMKA NRTALLAQQ
//
