ID A0A3Q1M5U2_BOVIN Unreviewed; 1294 AA.
AC A0A3Q1M5U2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Apoptotic chromatin condensation inducer 1 {ECO:0000313|Ensembl:ENSBTAP00000065688.1};
GN Name=ACIN1 {ECO:0000313|Ensembl:ENSBTAP00000065688.1,
GN ECO:0000313|VGNC:VGNC:25539};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000065688.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000065688.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000065688.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000065688.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000065688.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003582713.1; XM_003582665.4.
DR RefSeq; XP_003586558.1; XM_003586510.4.
DR Ensembl; ENSBTAT00000075843.1; ENSBTAP00000065688.1; ENSBTAG00000011571.5.
DR GeneID; 534600; -.
DR CTD; 22985; -.
DR VEuPathDB; HostDB:ENSBTAG00000011571; -.
DR VGNC; VGNC:25539; ACIN1.
DR GeneTree; ENSGT00710000106790; -.
DR Proteomes; UP000009136; Chromosome 10.
DR Bgee; ENSBTAG00000011571; Expressed in granulosa cell and 107 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1M5U2; baseline and differential.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12432; RRM_ACINU; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR034257; Acinus_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032552; RSB_motif.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46589; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR PANTHER; PTHR46589:SF1; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR Pfam; PF16294; RSB_motif; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 72..106
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..252
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..597
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..735
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..868
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1065
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1083
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1145
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1189..1275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1294 AA; 145886 MW; A66BBD46E3375AA5 CRC64;
MCRRKHPSTS GGTRGALSGN RGVDYGSGRG QLGTFEGRWR KLPKMPEAVG TDPSTSRKMA
ELEEVTLDGK PLQALRVTDL KAALEQRGLA KSGQKSALVK RLKGALMLEN LQKHSTPHAA
FQPNSQIGEE MSQNSFIKQY LEKQQELLRQ RLEREAREAA ELEGKSTSVS EEKGESDDEK
PRKGERRSSR VRQARAAKLS ECSQAAEEEE DQETPSRNLR VRADRNLKTE EEEEEEEEEE
EEEEEEDDDD EGQKSRDAPV LKQFKEEGEE IPIVKVEEVT DERPQTIRSQ EQEGLERGGR
VTRSQEEARR SHLARHQQEK EMKTASLEEE REIKSSKGLE EKSKSPSPPQ LTEDVAKAPV
VLQPELTASE EETPPPLLTK EASSPPPNTQ LQSEEEIEPM EGPAPPVLIQ LSPPNADAEA
RELLLSQHTV QLVGSLSPLS GPADTKVESP VEKVPEESVL PLVQKSAQAE SSAQKGLETE
SEKSTQPLPL KIEEFTLAKG ITEESLEQKE GRRASHALLP SHRLKQSADS SSSRSSSSSS
SSSRSRSRSP DSSGSQSHSP PRSKQRDGSG VRAHANPHDR SKVGSRSTSE SRSRSRSRSR
SASSNSRKSL SPGVSRDSST SYTETKDPSS GQEVAAPPLP QLQVLEPKER TSTPSSVQVR
LVSQPEPAAK HVTQRLQPDR GSPKKCEAEE AEPPAATQPQ TSETPTSHLP ESERIHHTVE
EKEEVTMDTS ENRPENEVPE PPMPIADQVS NDDRPEGNAE DEEKKESLLP KSFKRKISVV
SATKGVPAGN SDTEGGQPSR KRRWGASTAT TQKKPSISIT TESLKSLIPD IKPLAGQEAV
VDLHADDSRI SEDETERNGD DGTHDKGLKI CRTVTQVVPA EGQENGQREE EEEEKEPEAE
APVPPQVSVE VALPPPVEHE VKKVTLGDTL TRRSISQQKS GVSITIDDPV RTAQVPSPPR
GKISNIVHIS NLVRPFTLGQ LKELLGRTGT LVEEAFWIDK IKSHCFVTYS TVEEAVATRT
ALHGVKWPQS NPKFLCADYA EQDELDYHRG LLVDRPSETK TEEQGMPRPL HPPPPPPAQP
PQHPRAEQRE QERAVREQWA EREREMERRE RTRSEREWDR DKVREGPRSR SRSRDRRRKE
RAKSKEKKSE KKEKAQEEPP AKLLDDLFRK TKAAPCIYWL PLTDSQIVQK EAERAERAKE
REKRRKEQEE EEQKEREKEA ERERTRQLER EKRREHSRER DRERERDRER DRGDRDRERD
RERERGRERD RRDTKRHSRS RSRSTPVRDR GGRR
//
