ID   A0A3Q1M9U6_BOVIN        Unreviewed;       774 AA.
AC   A0A3Q1M9U6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Myotubularin related protein 10 {ECO:0000313|Ensembl:ENSBTAP00000066960.1};
GN   Name=MTMR10 {ECO:0000313|Ensembl:ENSBTAP00000066960.1,
GN   ECO:0000313|VGNC:VGNC:31737};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000066960.1, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000066960.1, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000066960.1,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000066960.1}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000066960.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR   AlphaFoldDB; A0A3Q1M9U6; -.
DR   Ensembl; ENSBTAT00000080507.1; ENSBTAP00000066960.1; ENSBTAG00000014422.6.
DR   VEuPathDB; HostDB:ENSBTAG00000014422; -.
DR   VGNC; VGNC:31737; MTMR10.
DR   GeneTree; ENSGT00940000156900; -.
DR   Proteomes; UP000009136; Chromosome 21.
DR   Bgee; ENSBTAG00000014422; Expressed in semitendinosus and 107 other cell types or tissues.
DR   ExpressionAtlas; A0A3Q1M9U6; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   CDD; cd13346; PH-GRAM_MTMR10; 1.
DR   CDD; cd14593; PTP-MTMR10; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR036004; MTMR10_PH-GRAM.
DR   InterPro; IPR030573; MTMR10_PTP.
DR   InterPro; IPR022587; MTMR12-like_C.
DR   InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR   InterPro; IPR030564; Myotubularin_fam.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR   PANTHER; PTHR10807:SF39; MYOTUBULARIN-RELATED PROTEIN 10; 1.
DR   Pfam; PF12578; 3-PAP; 1.
DR   Pfam; PF06602; Myotub-related; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          210..650
FT                   /note="Myotubularin phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51339"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   774 AA;  87917 MW;  2EE04675CE830075 CRC64;
     MFSLKPPRPT FRSYLLPPPQ TDDKINSEPK IKKLEPVLLP GEIVVNEVNF VRKCIASDTS
     QYDLWGKLIC SNFKISFITD DPMPLQKFHY RNLLLGEHDV PLTCIEQIVT LNDHKRKQKV
     LGPNQKLKFN PTELIIYCKD FRIVRFRFDE SGPESAKKVC LAIAHYSQPT DLQLLFAFEY
     VGKKYHNSAS KANGAPLGAG GGGSQKTPLF ETYSDWDREV KRTGASGWRV CSINEGYMIS
     TCLPEYFVVP SSLADQDLKV FSHSFVGRRM PFWCWSHSNG SALVRTALIR DVLQQRKIEQ
     RICNAITKSH PQRNDVYKSD LDKTLPNIQD IQVAFVKLKQ LCVNEPFEET EEKWLSSLEN
     TRWLEYVRAF LKHAAELVYV LESKRLSVVL QEEEGRDLSC IIASLVQVML DPYFRTITGF
     QSLIQKEWVM AGYPFLDRCN HLKRSEKEAP VFLLFLDTTW QLLEQCPAAF EFSETYLAVL
     HDSTRVALFG TFLFNSPHQR VQQSTEFAIS KNIQLGDEKG LKFPSVWDWS LQFTPKDRTL
     FHNPFYIGKS TPCVQNGSVK SFKRTKKSYS STLRGMPASL KNGIISEEEL RPRRNSLILQ
     VKPAPLETRD SQDWGAERFF QERASRPADL HGTILPHLSG AHIKLWKLCY FRWVPEAQIQ
     HGGFITAFHK LSLLADEVDV LSRALRQPRG GPMPAPGPEL APSRLYFCAG GPHDAPGTPD
     FLSSSFPFSP VGNLCRRSIS GTPLSKFLSG AKIWLSTETL KRGDQGGLPA RPEG
//