ID A0A3Q1MA56_BOVIN Unreviewed; 960 AA.
AC A0A3Q1MA56;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
GN Name=LOC101907335 {ECO:0000313|Ensembl:ENSBTAP00000070882.1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000070882.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000070882.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000070882.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000070882.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000070882.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1MA56; -.
DR Ensembl; ENSBTAT00000084216.1; ENSBTAP00000070882.1; ENSBTAG00000053486.1.
DR VEuPathDB; HostDB:ENSBTAG00000053486; -.
DR GeneTree; ENSGT00940000157963; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000053486; Expressed in omental fat pad and 13 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MA56; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 7.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071:SF24; SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130-RELATED; 1.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 7.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 7.
DR SUPFAM; SSF56487; SRCR-like; 7.
DR PROSITE; PS00420; SRCR_1; 3.
DR PROSITE; PS50287; SRCR_2; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..960
FT /note="SRCR domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018520953"
FT TRANSMEM 803..826
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..131
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 134..234
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 239..340
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 367..467
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 472..572
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 577..662
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 681..781
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 861..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 97..107
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 172..233
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 203..213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 265..329
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 278..339
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 309..319
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 392..456
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 405..466
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 436..446
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 497..561
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 510..571
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 541..551
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 706..770
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 719..780
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 750..760
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 960 AA; 102793 MW; 3CF96518F2496982 CRC64;
MALGRHLSLR GLCVLLLGTV VGGQVLELRL KDGAHHCEGR VEVKHQGEWG TVDDLEWTLK
DASVVCRQLG CGAAIGFPGG AYFGPGLGPI WLSYTSCEGV ESSVSDCRHS NIKDYRNASY
SHDEDAGVVC SGFVRLAGGD GPCSGRVEVY SGEAWIPVSD GNFTLLTAEV ICAELGCGKA
VSVQGHELFR ESSAWVWAEE FRCEGEEPEL WVCLRVPCPG GTCHHSGSAQ VVCSAYSEVR
LMTNGSSQCE GQVEMNISGR WRALCASHWS LANANVVCRQ LGCGVAISTP GGPHLVEGGD
QILTALFHCS GAESFLWSCP VTALGGPDCS HGNTASVICS GNQTQVLPQC NDSMAEPAGS
WASEESAPYC SGAGPCAGRV EILDQGSWGT ICDDGWDLDD AHVVCRQLGC GEALNATGSA
HFGAGSGPIW LDDLNCTGKE SHVWRCPSRG WGQHNCRHKQ DVGVICSEFL ALRMVSEDQQ
CAGWLEVFYN GTWGSVCCNP MEDITVSIIC RQLGCGDSAT LNSSVDLREG SRPQWVDRIH
CWKTDTSLWP CPSDPWNYTS CSPKEEAYIS CAGSRQLRLV DGGGPCAGRV EILNQGSWGT
ICDYSWSMKD ARVVCRQLGC GKALYATLSS SFGAGSGPIW CPSRGWGKHY CDHSEDAGVI
CSGRRPKSCP TAASCTDREK LRLRGGDSEC SGRVEVWHSG SWGTVCDDSW SLAEAEVVCQ
QLGCGQALEA VQAAGFGPGN GSIWLDEVWC RGRESSLWDC AEEPWEQSDC KHEEDAGVRC
SGETLPTTTA GTRTTSNSLP GIFSLPGVLC LILGSLLFLV LIILVTQLLR WRAEHRALSS
YEDALAEAVY EELDYLLTQK EGLGSPDQRT DVPAENYDNA EEVPVPGTPS ASQGNEEEVP
PEKEDGVRSS QTGSCLNFSR EAADPGEGEE SFWLLQGKKG DPGYDDVELS ALGTSPVTFS
//
