ID A0A3Q1MAN2_BOVIN Unreviewed; 1078 AA.
AC A0A3Q1MAN2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Myocardin related transcription factor B {ECO:0000313|Ensembl:ENSBTAP00000067288.1};
GN Name=MRTFB {ECO:0000313|Ensembl:ENSBTAP00000067288.1,
GN ECO:0000313|VGNC:VGNC:31489};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000067288.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000067288.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067288.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000067288.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067288.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_015315814.1; XM_015460328.1.
DR AlphaFoldDB; A0A3Q1MAN2; -.
DR SMR; A0A3Q1MAN2; -.
DR STRING; 9913.ENSBTAP00000067288; -.
DR Ensembl; ENSBTAT00000079282.1; ENSBTAP00000067288.1; ENSBTAG00000008728.6.
DR GeneID; 511461; -.
DR CTD; 57496; -.
DR VEuPathDB; HostDB:ENSBTAG00000008728; -.
DR VGNC; VGNC:31489; MRTFB.
DR GeneTree; ENSGT00950000182979; -.
DR InParanoid; A0A3Q1MAN2; -.
DR OMA; TMCNNTA; -.
DR OrthoDB; 2997330at2759; -.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000008728; Expressed in occipital lobe and 110 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MAN2; baseline.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:1902895; P:positive regulation of miRNA transcription; IEA:Ensembl.
DR GO; GO:0045844; P:positive regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0051145; P:smooth muscle cell differentiation; IBA:GO_Central.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF5; MYOCARDIN-RELATED TRANSCRIPTION FACTOR B; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 2.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 51..76
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 95..120
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 139..164
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 399..433
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..842
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1078 AA; 116256 MW; 19BB2283C8B71C92 CRC64;
MDHTGALDTE DELGPLAHLA PSPQSEAVAH EFQELSLQSS QHLPPLNERK NVLQLRLQQR
RTREQLVDQG IMPPLKSPAA FHEQIKSLER ARTENFLKHK IRSRPDRSEL VRMHILEETF
AEPSLQATQM KLKRARLADD LNEKIAQRPG PMELVEKNIL PVDSSVKEAI IGVGKEDYPQ
TQGDFSFDED SSDALSPDQP ASQESQGSAA SPSEPKVSES PSPVTTNTPA QFTPVSPAVP
EFLKTPTADQ PPPRSTAPVL PPSTTSSAKP GPALVKQSHP KNPNDKHRSK KCKDPKPRVK
KLKYHQYIPP DQKGERSEPH MDSNYARLLQ QQQLFLQLQI LSQQQQHYNY QTILPAPLKP
LNDKNNNSGN PALNTTTSNT PRQNTPAPVR KPGPLPSSLD DLKVSELKTE LKLRGLPVSG
TKLDLIERLK PYQEVNSSGP AAGGVTAVPT PAIVPSNPEV TVALPVTTRQ NSVTSSGSTF
KAELPPASSS SVAHVDSGSS PLPISPAPSE QSSLSAEDTS MADTFTEIMT MMSPSQFLCS
SPLRATSTED SLSPTSSTLS TLELDAAEKD RKLQEKEKQI EELKRKLEQE QKLVEVLKMQ
LEVEKRGQQQ QRPLEPPPPA STPAPSVSKA DQTRGPTAST TKDEAPLPDG PGPVAGQSLV
AKKAIVIKQE VPVAPAEPPS LVPQFYVSSQ GQPPAGVAQP QALLTTQTAQ LLLPVSIQGS
SVTSVQLPAG SLQLQTPPQT GLQTQPQIAA ATLSSGLAQA APQKQDAFPA RTLGQPQQAR
KVFTSSASST VLPYQRPPAP AVQQPFINKA NNSVLQPRST PLPSLQNGPS PPNKPGSPPP
PQQFVVQHSL FGNPVPKTKD PPRYEEAIKQ TRSAQSSLPE ISNAHSQQMD DLFDILIKSG
EISLPIKEEP SPISKMRPVT ASITTMPVST VVSRPPPQVQ MAPPISLEPM SSLSASLENQ
LEAFLDGTLP SANEIAPLQS GSEDREPFSL IEDLQNDLLS HSGVLDPSHS PMETAEAQFA
ASTPCLSLDL SDSNLDNMEW LDITMPGTSS GLTPLSATTP SMFSADFLDP QDLPLPWD
//
