ID   A0A3Q1MD80_BOVIN        Unreviewed;      1004 AA.
AC   A0A3Q1MD80;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Glutamate receptor interacting protein 2 {ECO:0000313|Ensembl:ENSBTAP00000072093.1};
GN   Name=GRIP2 {ECO:0000313|Ensembl:ENSBTAP00000072093.1,
GN   ECO:0000313|VGNC:VGNC:29652};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000072093.1, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000072093.1, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000072093.1,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000072093.1}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000072093.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1MD80; -.
DR   Ensembl; ENSBTAT00000070593.1; ENSBTAP00000072093.1; ENSBTAG00000011896.6.
DR   VEuPathDB; HostDB:ENSBTAG00000011896; -.
DR   VGNC; VGNC:29652; GRIP2.
DR   GeneTree; ENSGT00940000155615; -.
DR   Proteomes; UP000009136; Chromosome 22.
DR   Bgee; ENSBTAG00000011896; Expressed in biceps femoris and 91 other cell types or tissues.
DR   ExpressionAtlas; A0A3Q1MD80; baseline.
DR   CDD; cd00992; PDZ_signaling; 7.
DR   Gene3D; 2.30.42.10; -; 7.
DR   InterPro; IPR043545; GRIP1/2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR46227:SF4; GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2; 1.
DR   PANTHER; PTHR46227; GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP; 1.
DR   Pfam; PF00595; PDZ; 6.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM00228; PDZ; 7.
DR   SUPFAM; SSF50156; PDZ domain-like; 7.
DR   PROSITE; PS50106; PDZ; 7.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          53..136
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          153..239
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          253..337
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          419..494
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          520..604
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          619..701
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          903..985
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          16..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          65..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          702..830
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..383
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        768..794
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1004 AA;  107940 MW;  FFAA026477EEEBC3 CRC64;
     MLAVSLKWRL GVVRRRPKDN GPYTKGDKDT GAADGALARR RQSIPEEFRG VTTVELTKKE
     GSTLGLTISG GTDKDGKPRV SNLRPGGLAA RSDLLNVGDY IRSVNGIHLT RLRHDEIITL
     LKNVGERVVL EVEFELPPPA PENNPGIVSK TVDVSLLKEG NSFGFVLRGG AHEDGHKSRP
     LVLTYVRPGG PADREGSLKV GDRLLSVDGI PLQGASHATA LATLRQCSHE ALFQVEYDVT
     IPDTVANASG PLIVEITKTP GSALGISLTT GSHRNKPVIT IDRIKPASVV DRSGALHAGD
     HILSIDGTST EHCSLLEATK LLASVSEKVR LEILPAPQSR RPLKPSEAAL SSSPFSSPTV
     NHTFSCTNPS TLPRGSQPMS PRTTMGRRRP RRREHKSSLS LASSTVGPGG QIVHTETTEV
     VLCGDPLSGF GLQLQGGIFA TETLSSPPLV RFIEPDSPAE RCGLLQVGDR VLAINGIATE
     DGTMEEANQL LRDAALAHKV VLEVEFDVAE SVIPSSGTFH VKLPKRRGVE LGITISSASR
     KRGEPLVISD IKKGSVAHRT GTLEPGDKLL AIDNIRLDNC PMEDAVQILR QCEDLVKLKI
     RKDEDNSDEQ ETTGAISYTV ELKRYGGPLG ITISGTEEPF DPIVISGLTK RGLAERTGAI
     HVGDRILAIN SVSLKGRPLS EAIHLLQVAG ETVTLKIKKQ LDRPLTPRKS GSLSEASDAD
     EDPPEALKGG LLAARSSPTV PSVDSAVESW GGSATEGGFG GPGSYTAQTA ARAMTPQEWR
     SSWLRSSPPL TEPRRTSYTP GPADESVPEE EEEDWEPPTS PAPGPSREEG FWRTFGEALE
     DLESCGQSEL LRELEASIMT GTVQSVAPEG RPGHRPWRRS RELRASPEEM QELLLPTPVE
     MHKVTLHKDP VRSDFGFSVS DGLLEKGVYV HTVRPDGPAQ RGGLRPFDRL LQVNHVRTRD
     LDCCLTVPLL ADAGDVVELI ISRNPLAQTS RSPRAPGPSG PRML
//