ID A0A3Q1MHZ5_BOVIN Unreviewed; 907 AA.
AC A0A3Q1MHZ5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Semaphorin 6C {ECO:0000313|Ensembl:ENSBTAP00000070858.1};
GN Name=SEMA6C {ECO:0000313|Ensembl:ENSBTAP00000070858.1,
GN ECO:0000313|VGNC:VGNC:34443};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000070858.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000070858.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000070858.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000070858.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000070858.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3Q1MHZ5; -.
DR Ensembl; ENSBTAT00000084524.1; ENSBTAP00000070858.1; ENSBTAG00000007281.6.
DR VEuPathDB; HostDB:ENSBTAG00000007281; -.
DR VGNC; VGNC:34443; SEMA6C.
DR GeneTree; ENSGT00940000158641; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000007281; Expressed in choroid plexus and 94 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MHZ5; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF11; SEMAPHORIN-6C; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..907
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018521176"
FT TRANSMEM 587..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..509
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 500..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..788
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 96886 MW; 86D0AD6B13833EEA CRC64;
MPRAPHFMPL LLLLLLSIPH TQAAFPQDPL PLLTSDLHGI SPLSWFRGLE DDAVVAELGL
DFQRFLTLNR TLLVAARDHV FSFDLQAQEE GEGLVPNKYL TWRSQDVENC AVRGKLTDEC
YNYIRVLVPW DSQTLLACGT NSFSPVCRSY GITSLQQEGE ELSGQARCPF DATQSNVAVF
AEGSLYSATA ADFQASDAVV YRSLGPQPPL RSAKYDSKWL REPHFVHALE HGDHVYFFFR
EVSVEDARLG RVQFSRVARV CKRDMGGSPR ALDRHWTSFL KLRLNCSVPG DSTFYFDVLQ
ALTGPVNLYG RSALFGVFTT QTNSIPGSAV CAFYLDDIER GFEGKFKEQR SLDGAWTPVS
EDRVPSPRPG SCAGVGVAAL FPSSRDLPDD VLTFIKAHPL LDPAVPPATH QPLLTLTSRA
LLTQVAVDGM AGPYSNITVL FLGSNDGTVL KVLPPGGQSG GSEPILLEEI DAYSPSRSCL
ASQDPYCGWD SSRGCVDIRA PGGIDVDPTG NQESMEHDDC QDGATGSQSG TGDSTYVLLS
PGPSPETPSP PSDAHPRPQS STLGAHTQGV RRDLPPASAS RSVPIPLLLA CVAAAFALGA
SVSGLLVSCA CRRAHRRRSK DIESAGIPRP LSLRSLARLH GAGPEPPPPS KDGEGAQTPQ
LYTTFLPPPE GVPPPELACL PTPESTPELP VKHLRHAGGP WEWNQNGNNA KEGRSRARGG
NAAGGAAPRV LVKPPPPGCP GQAVEVTTLE ELLRYLHGPQ APRKEAEPPV AAPFTSRPLP
PEPSPTLFAG PSLLPRDCAP PRRLDVPPEG KCPAPAARPA LSAPAPRLGV GGSRKLPFSS
HRAPPALLTR VPSGGPSRYS GGAGRHLLYL GRPEGHRGRA LKRVEGREAP GAPEASLCRA
LLAGGRP
//
