ID A0A3Q1MJP2_BOVIN Unreviewed; 1743 AA.
AC A0A3Q1MJP2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Anaphase promoting complex subunit 1 {ECO:0000313|Ensembl:ENSBTAP00000069395.1};
GN Name=ANAPC1 {ECO:0000313|Ensembl:ENSBTAP00000069395.1,
GN ECO:0000313|VGNC:VGNC:25879};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000069395.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000069395.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000069395.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000069395.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000069395.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
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DR Ensembl; ENSBTAT00000075170.1; ENSBTAP00000069395.1; ENSBTAG00000027991.5.
DR VEuPathDB; HostDB:ENSBTAG00000027991; -.
DR VGNC; VGNC:25879; ANAPC1.
DR GeneTree; ENSGT00390000016757; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000027991; Expressed in spermatocyte and 108 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MJP2; baseline and differential.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 1.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 81..199
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 615..927
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1476..1561
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1595..1721
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
FT REGION 315..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1743 AA; 195272 MW; 53C56B61ED8E79CA CRC64;
MSNFYEERAT MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS
LQEVTIHEKQ KESWQLRKGV SEIGEEVDYD EELYMAGNMV IWSKGSKSQA LAVYKAFTVD
SPVQQALWCD FIISQDKSDK DYMERCICIL QSSCINMHSI EGKDYIASLP FQVANVWPTK
YGLLFERSSS SCEVPPGPPR EPLPTLFSML HPLDEITPVV CKSGSLFGSS RVQYVVDHAM
KIVFLHTDPS IVMTYDTVQG LHSVWALRRV KTEEGNVVLK FSEQGGTPQN VATSSSLTAH
LRSLSKGDSP VASPFQNYSS IHSQSRSASS PSLHSRSPSI SNMAALSRAH SPALGVYSFS
GVQRFNLSSH NQSPKRHSFS HSPSSNSNGS FLAPETEPIV PELCIDHLWT ETITRLRKKN
SQASKVFITS DLCGQKFLCY LVESELQLRC VKFQESNDKT QLIFGSVTNI QAKDAAPVEV
NNGVKSLCII VKPYAKKTCN FFIQISQKCF TCCIYDPVQV LVSPVPELRD SSKLHDSLYT
EDCTFQQLGT YIHSIRDPVR NRVTLVIQTC LQAIKFILPK EIAVQMLVKW YSVHSAPGGP
SDHSEWNLFV TCLMNMMGYN TDRLAWTRNF DFEGSLSPVI APKKARPSET GSDDDWEYLL
NSDYHQNVES HLLNRSLCLS PLEVSQMKDE DFSQNLSLDS STLLFTHIPA IFFVLHLVYE
ELKLNTLMGE GVRSLVELLV QLARDLKLEP YIDHYYRDYP TLVRTTGQVC AIDQGQTGSM
QYPPFFTPEP PSIYQWVSSC LKGEGVPPYP YLPGICERGR LVVLSIALYI LGDESSLSDE
SSQYLSRISI GKSSLLTLFG GLGQWLSLTE EFSPFPPSQG FTLRDLETLP FGIALPIRDA
IYHCREQPAS DWPEAVCLLI GRQDLSKQAC EGNLPKGKSV NVPSGTETEE EDDGMNDMNQ
EVMSLIWSED LRVQDVRRLL QSAHPVRVNV VQYPELSDHE FIEEKENRLL QLCQRTMALP
VGRGMFTLFS YHPVPTEPLP IPKLNLTGRA PPRNTTVDLN SGNIDVPPNM TSWASFHNGV
AAGLKIAPAS QIDSAWIVYN KPKHAELANE YAGFLMALGL NGHLTKLATL NIHDYLTKGH
EMTSIGLLLG VAAAKLGTMD MSVTRLLSIH IPALLPPTST ELDVPHNVQV AAVVGIGLVY
QGTAHRHTAE VLLAEIGRPP GPEMEYCTDR ESYSLAAGLA LGMVCLGHGS NLIGMSDLNV
PEQLYQYMVG GHRRFQAGMH REKHKSPSYQ IKEGDTINVD VTCPGATLAL AMIYLKTNNS
VTAWPIADWL RAPDTMYLLD FVKPEFLLLR VCNCYFLLDT LLSEFSTWNL NFIIRENIFS
EFLSCPYNLE TCLSVVLLSL AMVMAGSGNL KVLQLCRFLH MKTGGEMNYG FHLSHHRPLG
LPLLCCLPLS RPFVFSVNRY HLQALRHLYV LAAEPRLLVP VDVDTNMPCY ALLEVTYKGT
QWYEQTKEEL MAPTLLPELH LLKQIKVKGP RYWELLIDLS KGTQHLKSIL SKDGVLYVKL
RAGQLSYKED PMGWQSLLAQ TVANRNSEAR AFKPETISTF TSDPALLSFA EYFCKPTVNK
QELLDLFSSV LYECVTQETP EMLPAYIAMD QAVRRLGRRE MSETSDLWQI KLVLEFFSSR
SHQERLQNQP NRGLFMNSEF LPVVKCTTDN TLDQWLQGES STAPLSFELH WVSGLSVFTC
FPW
//
