ID   A0A3Q1MJZ7_BOVIN        Unreviewed;      1051 AA.
AC   A0A3Q1MJZ7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Nuclear export mediator factor {ECO:0000313|Ensembl:ENSBTAP00000071171.1};
GN   Name=NEMF {ECO:0000313|Ensembl:ENSBTAP00000071171.1,
GN   ECO:0000313|VGNC:VGNC:32004};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000071171.1, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000071171.1, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071171.1,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000071171.1}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071171.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   AlphaFoldDB; A0A3Q1MJZ7; -.
DR   Ensembl; ENSBTAT00000071470.1; ENSBTAP00000071171.1; ENSBTAG00000004934.6.
DR   VEuPathDB; HostDB:ENSBTAG00000004934; -.
DR   VGNC; VGNC:32004; NEMF.
DR   GeneTree; ENSGT00390000018516; -.
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000004934; Expressed in oocyte and 109 other cell types or tissues.
DR   ExpressionAtlas; A0A3Q1MJZ7; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          529..639
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          950..1041
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          420..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          694..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          745..954
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          296..340
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          484..511
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        758..776
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        779..806
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        807..854
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..902
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        909..944
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1051 AA;  119700 MW;  7F9974868B126B0E CRC64;
     MKTRFSTVDL RAVLAELNAS LLGMRVNNVY DVDNKTYLIR LQKPDFKATL LLESGIRIHT
     TEFEWPKNMM PSSFAMKCRK HLKSRRLVSA KQLGVDRIVD FQFGSDEAAY HLIIELYDRG
     NIVLTDYEYL ILNILRFRTD ESDDVKFAVR ERYPIDHARA AEPLLTLERL TEILAGAPKG
     ELLKRVLNPL LPYGPALIEH CLIENGFPAN VKVDEKFESK DVEKVLVCLQ KAEEYMKTTS
     SFNGKGYIIQ KREIKPSLEV DKPTEDILTY EEFHPFLFSQ HSQCPYIEFE SFDKAVDEFY
     SKIEGQKIDL KALQQEKQAL KKLDNVRKDH ENRLEALQQA QEIDKLKGEL IEMNLQIVDR
     AIQVVRSALA NQIDWTEIGL IVKEAQAQGD PVANAIKELK LQTNHVTMLL RNPYLLSEEE
     DDDVDGDIST EKNEPEPPKG KKKKQKNKQL QKPQKNRPLL VDVDLSLSAY ANAKKYYDHK
     RYAAKKTQKT VEAAEKAFKS AEKKTKQTLK EVQTVTSIQK ARKVYWFEKF LWFISSENYL
     IIGGRDQQQN EIIVKRYLTP GDIYVHADLH GATSCVIKNP TGEPIPPRTL TEAGTMALCY
     SAAWDARVIT SAWWVYHHQV SKTAPTGEYL TTGSFMIRGK KNFLPPSHLM MGFSFLFKVD
     ESCVWRHRGE RKVRVQDEDM ETLASCTSEL ISEEMEQLAD GGESSSEEDK DELHETPVEV
     ELVTQVDQED VTIQSGGNEL NELIQEESSE DEGESEGVVK DQEPVGEMKD EGEETLNYPD
     TSIDLSHLQS QRSLQKLSSK EESSNMSDSK LQSRRHLSAK ERREMKKKKL PNDSGDLEMT
     EAKDKEKENA LHIETHQNTS KNVPVVQPMK RGQKSAGSNK EEKGKKGKKG KIKDEPVKKQ
     PQKPRGGPRV SDSIKKETPS LEITTHELQD LAVDEPHDDK EEQDVDQQGN EENLFDSLTG
     QPHSEDVLLF AIPICAPYTT MTNYKYKVKL TPGVQKKGKA AKTALNSFMH SKEATAREKD
     LFRSVKDTDL SRNIPGKVKV SAPNLLNVKR K
//