ID A0A3Q1MME3_BOVIN Unreviewed; 501 AA.
AC A0A3Q1MME3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Syntrophin gamma 1 {ECO:0000313|Ensembl:ENSBTAP00000072961.1};
GN Name=SNTG1 {ECO:0000313|Ensembl:ENSBTAP00000072961.1,
GN ECO:0000313|VGNC:VGNC:35085};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000072961.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000072961.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000072961.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000072961.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000072961.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the syntrophin family.
CC {ECO:0000256|ARBA:ARBA00010798}.
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DR AlphaFoldDB; A0A3Q1MME3; -.
DR SMR; A0A3Q1MME3; -.
DR STRING; 9913.ENSBTAP00000072961; -.
DR Ensembl; ENSBTAT00000068550.1; ENSBTAP00000072961.1; ENSBTAG00000002448.6.
DR VEuPathDB; HostDB:ENSBTAG00000002448; -.
DR VGNC; VGNC:35085; SNTG1.
DR GeneTree; ENSGT00950000182863; -.
DR InParanoid; A0A3Q1MME3; -.
DR OMA; YVTRYLW; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000002448; Expressed in occipital lobe and 24 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MME3; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016010; C:dystrophin-associated glycoprotein complex; IBA:GO_Central.
DR GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR015482; Syntrophin.
DR PANTHER; PTHR10554:SF2; GAMMA-1-SYNTROPHIN; 1.
DR PANTHER; PTHR10554; SYNTROPHIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 41..124
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 267..374
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 501 AA; 55995 MW; F0429E43531DFA7E CRC64;
NSCLTLCELH LRLHLARDIL MIQEQDVTCV SGEPFYSGER TVTIRRQAVG GFGLSIKGGA
EHNIPVVVSK ISKEQRAELS GLLFIGDAIL QINGINVRKC RHEEVVQVLR NAGEEVTLTV
SFLKRAPAFL KLSLNEDCAC APSDQSSGTS SPLCDSGLHL NYHPNNTDTL SCSSWPASPG
LRWEKRWCDL RLIPLLHSRF SQYLPGTDLS RQNAFQVTAV DGVCSGVIQC LSAEDCGEWL
QAIATNISSL TKHNIKKINR NFPVNQQIVY MGWCEMREQD PLQDRVYSPA FLALRGSCLY
KFLAPPVTTW DWTRAEKTFS VYEIMCKILK DSDLLDRRRH CFTVQSESGE DLYFSVELDS
DLAQWERAFQ TATFLEVERI QCKTYACVLE GHLMGLTIDF STGFICFDAA TKVVLWRYKF
SQLKGSSDDG KSKIKFLFQN PDTKQIEAKE LEFSNLFAVL HCIHSFFAAK VACLDPLFLG
SQAAASAASS SGVPSKAKYM T
//
