ID A0A3Q1MQE4_BOVIN Unreviewed; 558 AA.
AC A0A3Q1MQE4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Microtubule-associated protein {ECO:0000256|RuleBase:RU000686};
GN Name=MAP2 {ECO:0000313|Ensembl:ENSBTAP00000071956.1,
GN ECO:0000313|VGNC:VGNC:31182};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000071956.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000071956.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071956.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000071956.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071956.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|RuleBase:RU000686}.
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DR RefSeq; XP_010800540.1; XM_010802238.2.
DR AlphaFoldDB; A0A3Q1MQE4; -.
DR Ensembl; ENSBTAT00000080758.1; ENSBTAP00000071956.1; ENSBTAG00000018130.6.
DR GeneID; 281294; -.
DR CTD; 4133; -.
DR VEuPathDB; HostDB:ENSBTAG00000018130; -.
DR VGNC; VGNC:31182; MAP2.
DR GeneTree; ENSGT00940000156597; -.
DR Proteomes; UP000009136; Chromosome 2.
DR Bgee; ENSBTAG00000018130; Expressed in prefrontal cortex and 106 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1MQE4; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR027324; MAP2/MAP4/Tau.
DR InterPro; IPR001084; MAP_tubulin-bd_rpt.
DR InterPro; IPR018459; RII-bd_1.
DR PANTHER; PTHR11501; MICROTUBULE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR11501:SF15; MICROTUBULE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF10522; RII_binding_1; 1.
DR Pfam; PF00418; Tubulin-binding; 4.
DR PROSITE; PS00229; TAU_MAP_1; 2.
DR PROSITE; PS51491; TAU_MAP_2; 4.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU000686};
KW Cytoskeleton {ECO:0000256|RuleBase:RU000686};
KW Microtubule {ECO:0000256|RuleBase:RU000686};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 85..103
FT /note="RII binding"
FT /evidence="ECO:0000259|Pfam:PF10522"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 558 AA; 58867 MW; 11467B5F9D5F0930 CRC64;
MADDRKDEAK APHWTSAQLT EASAQPHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE
HGSQGTYSNT KENGINGELT STDRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQPKDQP
PALPLAAEET ANLPPSPPPS PASEQTVPVE EAAGAESAQA PSVFKQAKDK VSNSTLSKIP
ALQGSTKSPR CSSACPSATK RATFSDSLFI QPTSAGSTDR LPYSESGNKD GVTKSPEKRS
SLPRPSSILP PRRGVSGDRD ENSFSLNSSI SSARRTTRSE PIRRAGKSGT STPTTPGSTA
ITPGTPPSYS SRTPGTPGTP SYPRTPHTPG TPKSAILVPS EKKVAIIRTP PKSPATPKQL
RLINQPLPDL KNVKSKIGST DNIKYQPKGG QVRILNKKID FSKVQSRCGS KDNIKHSAGG
GNVQIVTKKI DLSHVTSKCG SLKNIRHRPG GGRVKIESVK LDFKEKAQAK VGSLDNAHHV
PGGGNVKIDS QKLNFREHAK ARVDHGAEII TQSPGRSSVA SPRRLSNVSS SGSINLLESP
QLATLAEDVT AALAKQGL
//
