ID A0A3Q1N033_BOVIN Unreviewed; 1047 AA.
AC A0A3Q1N033;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=CAP-Gly domain containing linker protein 2 {ECO:0000313|Ensembl:ENSBTAP00000061932.1};
GN Name=CLIP2 {ECO:0000313|Ensembl:ENSBTAP00000061932.1,
GN ECO:0000313|VGNC:VGNC:27445};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000061932.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000061932.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000061932.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000061932.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000061932.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001179049.1; NM_001192120.1.
DR RefSeq; XP_005225103.1; XM_005225046.3.
DR RefSeq; XP_015315902.1; XM_015460416.1.
DR AlphaFoldDB; A0A3Q1N033; -.
DR SMR; A0A3Q1N033; -.
DR STRING; 9913.ENSBTAP00000061932; -.
DR PaxDb; 9913-ENSBTAP00000015759; -.
DR Ensembl; ENSBTAT00000080157.1; ENSBTAP00000061932.1; ENSBTAG00000011875.6.
DR GeneID; 506908; -.
DR KEGG; bta:506908; -.
DR CTD; 7461; -.
DR VEuPathDB; HostDB:ENSBTAG00000011875; -.
DR VGNC; VGNC:27445; CLIP2.
DR GeneTree; ENSGT00940000159426; -.
DR InParanoid; A0A3Q1N033; -.
DR OrthoDB; 2914056at2759; -.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000011875; Expressed in prefrontal cortex and 105 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1N033; baseline.
DR GO; GO:0005938; C:cell cortex; IBA:GO_Central.
DR GO; GO:0035371; C:microtubule plus-end; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0051010; F:microtubule plus-end binding; IBA:GO_Central.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IBA:GO_Central.
DR Gene3D; 6.10.250.1080; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916:SF10; CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2; 1.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR Pfam; PF01302; CAP_GLY; 2.
DR SMART; SM01052; CAP_GLY; 2.
DR SUPFAM; SSF74924; Cap-Gly domain; 2.
DR PROSITE; PS00845; CAP_GLY_1; 2.
DR PROSITE; PS50245; CAP_GLY_2; 2.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A3Q1N033};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 98..140
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 238..280
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1047
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 353..524
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 563..611
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 674..799
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 852..886
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 935..962
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 18..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1021..1036
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1047 AA; 115864 MW; 38B591898F2B2489 CRC64;
MQKPSGLKPP GRGGKHSSPM GRTSTGSASA STTVAPTGSK EGSPLHKQAS GPPAAAPAAP
EKPGAKAAEV GDEFAGDFVV GERVWVNGVK PGVVQYLGET QFAPGQWAGV VLDEPVGKND
GAVGGVRYFE CPALQGIFTR PSKLTRQPAA EGSGSDAHSV ESLTAQNLSL HSGTATPPLT
SRVIPLRESV LNSSVKTGNE SGSNLSDSGS VKRGDKDLRL GDRVLVGGTK TGVVRYVGET
DFAKGEWCGV ELDEPLGKND GAVAGTRYFQ CPPKFGLFAP IHKVIRIGFP STSPAKAKKT
KRMAMGVSAL THSPSSSSIS SVSSVASSVG GRPSRSGLLT ETSSRYARKI SGTTALQEAL
KEKQQHIEQL LAERDLERAE VAKATSHICE VEKEIALLKA QHEQYVAEAE EKLQRARLLV
ESVRKEKVDL SNQLEEERRK VEDLQFRVEE ESITKGDLET QTQLEHARIG ELEQNLLLEK
AQAERLLREL ADNRLTTVAE KSRVLQLEEE LSLRREEIEE LQQCLLHSGP PPADHPEAAE
TLRLRERLLS ASKERQRESG LLRDKYEKAL RAYQAEVDKL RAANEKYAQE VVDLKAKVQQ
ATSENMGLMD NWKSKLDSLA SDHQKSLEDL KATLNSGPGA QQKEIGELKA VMEGIKMEHQ
LELGNLRAKH DIETAVHVKE KEGLRQKLQE AQEELAAVQQ HWCAQLEVQA SQHRLELQEA
QDQCRDAELR VRELEKLDVE YQGQAQAIEF LKEQISLAEK KMLDYELLQR SEAQSKQEAE
RLQEKLLVTE NRLQAVESLC SAQHTHMIES NDISGEKIRM KETVEGLQDK LNKRDKEVTA
LTSQTEMLRA QVSALESKCR SGEKKVDTLQ KEKRRLEAEL EAVSRKTHDA SGQLVLISQE
LLRKERSLNE LRVLLLEANR HSPGPERDLS REVHKAEWRI KEQKLKDDIR GLREKLTGLD
KEKSLSDQRR YSLIDPSSSS APELLRLQHQ LISTEDALRD ALDQAQQVER LVEAMRSCPD
KSQAIGNSGS ANGIHQQDKG HKQEDKH
//
