ID A0A3Q1N233_BOVIN Unreviewed; 286 AA.
AC A0A3Q1N233;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Thymidine kinase 2 {ECO:0000313|Ensembl:ENSBTAP00000063251.1};
GN Name=TK2 {ECO:0000313|Ensembl:ENSBTAP00000063251.1,
GN ECO:0000313|VGNC:VGNC:103723};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000063251.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000063251.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000063251.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000063251.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000063251.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_015322840.1; XM_015467354.1.
DR RefSeq; XP_015331296.1; XM_015475810.1.
DR AlphaFoldDB; A0A3Q1N233; -.
DR Ensembl; ENSBTAT00000080732.1; ENSBTAP00000063251.1; ENSBTAG00000005152.5.
DR GeneID; 615457; -.
DR CTD; 7084; -.
DR VEuPathDB; HostDB:ENSBTAG00000005152; -.
DR VGNC; VGNC:103723; TK2.
DR GeneTree; ENSGT00940000158005; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000005152; Expressed in liver and 105 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1N233; baseline.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF35; THYMIDINE KINASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 93..269
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
SQ SEQUENCE 286 AA; 33029 MW; 0D7AADB356340446 CRC64;
MESIIYSVNK AEHIGGLDMP TASGRQFWFQ GIDTSLPPST EGVSQVLLEN ISRPGSKHNN
DRRVSYLKSR LKIGFLSFLD KDRENEKEKK SVVCVEGNIA SGKTTCLEFF SNSTDIEVLT
EPVPKWRNVR GHNPLGLMYQ DACRWGFTLQ TYVQLTMLDQ HTRPQTLPVR LMERSIYSAR
YVFVENLYRS GKMPKVDYVV LSEWFDWIVR NIDVSIDLIV YLRTTPETCY QRLKMRCREE
EKVIPLEYLD AIHHLYEEWL IKGSLFPVAA PVLGVAGPEP HCTFSW
//
