ID A0A3Q1ND84_BOVIN Unreviewed; 657 AA.
AC A0A3Q1ND84;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
GN Name=LRRFIP2 {ECO:0000313|Ensembl:ENSBTAP00000069438.1,
GN ECO:0000313|VGNC:VGNC:31035};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000069438.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000069438.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000069438.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000069438.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000069438.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1ND84; -.
DR Ensembl; ENSBTAT00000071605.1; ENSBTAP00000069438.1; ENSBTAG00000016760.6.
DR VEuPathDB; HostDB:ENSBTAG00000016760; -.
DR VGNC; VGNC:31035; LRRFIP2.
DR GeneTree; ENSGT00530000063564; -.
DR Proteomes; UP000009136; Chromosome 22.
DR Bgee; ENSBTAG00000016760; Expressed in cardiac atrium and 107 other cell types or tissues.
DR ExpressionAtlas; A0A3Q1ND84; baseline and differential.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR Pfam; PF09738; LRRFIP; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT REGION 224..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 301..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 506..533
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 559..649
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 238..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 74821 MW; 4E4A86D36609B10E CRC64;
MRELERQQKE HSHHSFDRKW GQIQKWLEES ERARSSHRSS HRRPSLGVED ALSIRSLGSH
RYDALKDRSS RLSSLNHSYS HSYGMKKRSS GSHKDPLSGL YFDQRNYSSL RHSKPTSAYY
SRQSSSLYSD PLATSKSYRV SLYNGGLYNP YGSRTPSEYS FHSSRASSSR SSPVFLDDDT
ASIASSGCAS RGRRDSVVSA ADYFSRSNRR GSVVSDVDDV SIPDLTSLDE KSDKQYAENY
TRPSSRNSAS ATTPLSGNSS RRGSGDTSSL IDPDTSLSEL RDIYDLKDQI QDVEGRYMQG
LKELKESLSE VEEKYKKAMV SNAQLDNEKN NLIYQVDTLK DVIEEQEEQM AEFYRENEEK
SKELERQKHM CSVLQHKMDE LKEGLRQRDE LIEEKQRMQQ KIDTMTKEVF ELQETLLWKD
KSIRALEKLK EHAGCLRSER DALREELAKL KAAVEVGEKH GLVIIPDGTP NGDVHQEPAV
GAITVVSQEA AQVLESAGEG PLDVRLRKLA GEKEELLSQI RKLKLQLEEE RQKCSGRDGT
AGDLAELQNG SDLQLIEMQR DANRQISEYK FKLSKAEQDI TTLEQSISRL EGQVLRYRTA
AENAEKVEDE LKAEKRKLQR ELRTALDKIE EMEMTNSHLA KRLEKMKANR TALLAQQ
//
