GenomeNet

Database: UniProt
Entry: A0A3Q1NIE5_BOVIN
LinkDB: A0A3Q1NIE5_BOVIN
Original site: A0A3Q1NIE5_BOVIN 
ID   A0A3Q1NIE5_BOVIN        Unreviewed;      3171 AA.
AC   A0A3Q1NIE5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   07-OCT-2020, entry version 10.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSBTAP00000071796};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSBTAP00000071796,
GN   ECO:0000313|VGNC:VGNC:27176};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000071796, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000071796, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071796,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000071796}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000071796};
RG   Ensembl;
RL   Submitted (JAN-2019) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   Ensembl; ENSBTAT00000079772; ENSBTAP00000071796; ENSBTAG00000024449.
DR   VGNC; VGNC:27176; CENPF.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   ExpressionAtlas; A0A3Q1NIE5; baseline and differential.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 4.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 4.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1800..1919
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2006..2145
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2188..2327
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2370..2509
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          3027..3070
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          211..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1241..1262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1712..1749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2947..3171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..706
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          839..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..933
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          937..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1036..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1089..1109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1118..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1209..1229
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1283..1324
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1336..1356
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1401..1421
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1546..1616
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1797..1824
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1860..1904
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1912..1953
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1982..2009
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2017..2160
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2171..2191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2199..2335
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2381..2517
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2525..2660
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2693..2741
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2746..2773
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2796..2882
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2893..2920
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        475..493
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1712..1730
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2975..2989
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2997..3011
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3012..3028
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3056..3070
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3085..3116
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3141..3156
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3171 AA;  364120 MW;  8B5F8A2FC7CE0E53 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN SCLTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQTIPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS NTLKTPVRRD
     FSASHFSGEQ EVTPSRSTLQ IGKTDANSSF CDNSSNSHLL DQLKAQNQEL RSKMSELELR
     LQGQEKEMKG QVNKLQELQL QLEKAKVELN EKEKVLNKNR DELVRTTSQY DQASAKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECTQMKAR
     LTQELQQAKN TYNILQAELD KVTSVKQQIE KKLEEFKQNF SKTEQALQAS QTKENELRRS
     SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQCLSQSQ NFAEEMKAKN TSQETMLRDL
     QEKINQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK TERESEALLS
     ALELKKKEYE ELKEEKTLFS RWKSENEQLL NQMESEKESL QSKVNHLETC LKTQQIKSHE
     YNERVRTLEM ERENLNVEIR NLQNVIDSKT AEAETQKRAY GELQQKAEFS DQKHEKEIEN
     MCLKISHLTG QVEDLEHKLQ LLSSEIMDKD QRYQDLHAES ESLRDLLKSR DSSAMTIEPH
     QRSRLAFEQQ SALNNSFANI IGEQESVPSE RSRCHVATDQ SPKSSSMLQN RVVSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSVHQNVVA
     ETLAALESKE RELQLLNEKL ETEQAETGEL KKNNHLLQES LKELQFLSET LSLEKKELNS
     IISLNKKDIE ELTQENGTLK EINATLTQEK MNLLQKTESF SNCIDERDRS ISELSNQYKQ
     ERLTLLQRCE ETGNAFQDLS EKYKAVQEKN SKLECLLSEC TGVCEDRKNE LGQLKETFAR
     EHQAFVSQLA LAEERNQNLI VELETVQQAL QSEITDIQNS SKRETDGLKQ EIMNLKEEQN
     KMQQEVSALL QENEHLMELM KTKHEHQCLE LEPIQDSEKE EREINTCHLQ LPMDLDVKDT
     SPDTCNAQLV QVESKVRNME LKLQKSEKEE CLQYELQTRE LETEDLQQDP QSQDISGLGD
     SEIDPEEKYI SVLQELSTSQ QDNAHLQCSL QTAMNKLNEL EKMCEALQVE KSELISELND
     SRSECITATS KMAEEVGKLV NEVETLNDEN ALLQGELVEE TPEGEFGEQQ DEQTSVNLNP
     LDDSNFYEHL TMSSKEVQMH FAELQEKFSS LQSEHKILHE QHCLMSSKMS ELQSYVDTLK
     AENSVLSMSL RSSQGDLVKE VPPGPGEEHL LSLSFSCVTD SPGKASLGES SFYKDLLEHT
     TETSLLNNLE GTVSANQSNV EEVSCSSLEE ENLTEKEIPS VPLRSARELE TLCQTYLESL
     KQLEEEIESQ GITKNKEIKE LKELLSSSRE ELDDLRKQYL SENEQWQQKL TDVTAEMESK
     LAAEKRHAEH LTLELEVARL QLQGLDLSSR SLLGTDIEDA ILGGNDSCDI RESEEYISET
     KERTPKHEIH QICEKDVQQD LSLEMEKITK TGATKLTEEW SREQSSESSH ETPVEDPAQG
     CSGCISELSL SGPNASVPRD FLENQREESS GGLTSNLEMV TSKFPHEGIE DDVAKVTDNW
     REKCLQVENE LQRIQSEKDS MEHHALSAEA SLEAVQTEKL YLEKDNENKQ TVITCLEEGL
     SVVTSERDQL RGELDTLSKE NQELDQMSEK MKEKIRELES HQSECLHLQE WLQSLEKDSQ
     ALSLVRSELE NQIEQLNKEK DSLVWESESL QTKLSESEHE KLAITKALEA ALMEKGEVAV
     RLSSTQEEVH QLRKGIEKLR VRIEADEKKQ LHVSEKLKES ERRNDSLQDK VETLERELQM
     AEENQELVIL DAENCKAEVE TLKTQIELMT ERLKDLELDL VTIRSEKENL LKQLQEKQGQ
     ASELDTLLSS LKNLLEEKER EKIQTKEEAK SAVEMLQTQL RELTEEIAAL CDDQETWKVE
     EQSLDSPAQE VQQLRNNIEK LKVHLDIDKK KQLQILEKLK ESEHQADFLK DTVENLEREL
     KLSGENQEHV TLEAEKSKAE VETLKATVEK MDQNLRGLQL DLVNIRSEKE DLTKELQKEQ
     SRVSELETLN SSFENLLREK EQEKVQMKEE SKAAVEMLQT QLKELSEEVA ILCVDQETWK
     VEEQSLDSPL EEIQQLRNNI GKLKVCLDAD KKQQLHILEK LKESEHQADF LKDTVENLER
     ELKLSGENQE HVTLEAEKSK AEVETLKATV EEMDQNLRGL QLDLVNIRSD KEDLTKELQK
     EQSRVSELET LNSSFENLLR EKEQEKVQMK EESKAAVEML QKELEELNEK MAALGNDQET
     RKVKEQSLSS QVDSLEHEKA QLLQDLDDAK SNYMILQSSV NDLIQEVEDG KQKLEKKDEE
     ISILKSQTRD QEQLVSKLSQ MEGEQQLWKK QKADLENLMV ELEQKIQVLQ SKNDALQDTL
     EALQNSSRNL EKELELTKLE KMSFVEKVNT MTVKETELQK EIHAVIQKTV ALKEEFSGEK
     NRLMEELNLM LEEVKSSKGQ LKELMLENSE LKKSLDCVHK DRMEEQGKMR GEIAEYQLRL
     QEAENKHQAL LLDTNKQHEM EIQTYREKLT SKEECLSSQK VEIDLLKSSK EELNNSLKAT
     TEILEELKKT KMENLKHADK LKKENDRAQS KIKLLVKSCK QLEEEKVMLQ KELSHLEAAQ
     EKQRADTVVD ANVDELITEM KELKETLEEK TKEADEYLDK YCSLLISHEK LEKAKEMLET
     QVARLSSQQS KLNLRRSPLV NSLAPGPSPV PSATEKKLPS GQNKSSGKRQ RSSGIREDGG
     ETTPSTPETF SKKSRKAIRS GTHLAEDAED AEFEPEGLPE VVKKGFADIP TGKTSPYILR
     RTTMATRTSP RLAAQKLAAS PPSLDKENLT ETSKPTAGGS RSQKVKVSQQ SPVDSGTAFR
     DPIGRSLSIS NLPERSPVGS PREGLRAKRG RHAPSPESSL ESKGSENCRV Q
//
DBGET integrated database retrieval system