ID A0A3Q2C678_CYPVA Unreviewed; 1139 AA.
AC A0A3Q2C678;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Potassium channel subfamily T member 2-like {ECO:0000313|Ensembl:ENSCVAP00000000077.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000000077.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000000077.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q2C678; -.
DR STRING; 28743.ENSCVAP00000000077; -.
DR Ensembl; ENSCVAT00000015669.1; ENSCVAP00000000077.1; ENSCVAG00000023382.1.
DR GeneTree; ENSGT00940000166551; -.
DR OMA; MYKWRSY; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF35; POTASSIUM CHANNEL SUBFAMILY T MEMBER 2-LIKE; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 101..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 208..273
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 430..525
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 608..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1113..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 964..979
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1000
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1113..1130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1139 AA; 129437 MW; 1320B5C72CF145ED CRC64;
MVELEKEVLP LPPRYRFRDL LLGDWQTDDR VQVEFYVNEN TFKERLKLFF IKNQRSSLRV
RMFNFALKVL SCLLYIVRVL LDNPQEDRQD WKLIIWVDRP LPLWALQVRY ILLSFFLTSV
CGVCFQGNVW EQVLRVPFIL EMISTVPFMI TVILPSLRNL FIPVFLNCWL AKHALENMIN
DLHRAIQRTH SAMFNQVVIL ISTLVCLMFT CICGIQHLER AGNNLTLFDS LYFCVVTFST
VGFGDVTPQI WPSQLLVVIM IFVALIVLPI QFEQLAFLWM ERQKSGGNYS RYRAQTEKHV
VLCVSCLKID LLMDFLNEFF AHPRLQDYYV VILCPAEMDV QVRRVLHVPL WALRVIYLQG
SALKDQDLMR AKMDDAEACF ILSNRFEVDR IAADHQTILR AWAVKDFAPN CPLYVQILKP
ENKFHVKFAD HVVCEEEFKY AMLALNCVCP GTSTLITLLI HSSRGQNGGA GSSDQWHRTY
RRCSANEVHH IRLEESKFFG EYLGKSFTFA SFHAHKKFGV CLIGVRRLDT TNILLNPGPC
HIMGASDTCF YINISKEENS AFVRGQREPS WGGAGGNSRG VHQSIYHGLT RLPVHSIIAS
MGTVAIDLQD SSDSSPEGQD PVGTGLSSGR GTDDRRHSIA PVLELVDGVN NPTFDLLGEQ
SEDEVGEEDV NVSLCCRWVK GYPLNSPYIG SSPALCHLLQ EKMPFCCLRM DKPCPHIPFE
DARSYGFKNK LIIVSAESAG NGLYNFIVPL RAYYRTRKEL KPIVLLLESI LDSLLRCGIT
FADTMVVFDK ESSMIAEEDY MADAKTIVNV QTLFRLFPAL SIITELTHPA NMRFMQFKVK
DHYSLALSKL EKKEREKGSN LVFMFRLPFA AGKVFSVSML DTLLYQSFVK DYMISITRLL
LGLDSMPGSG FLCAMKITED DLWIRTYGRL YQKLCSSTGD IPIGIYRTEA HKLPVSESQV
SITVEDYEDT REPREPLLSR TGTHRNSTSS EPISTSSHTS DHPLLRRKSM QWARRLSRKG
GRGSSGAKGG PGSAAERISQ QRLNLFRRSE RQELNSLVRT RMKHLGLSPT GFNGMTDQGN
RLSYILINPS PDTRLDLNDV VYLIRPDPLS LVPNQGSSRK CSAGLSESHR FDTQDSTHL
//
