ID   A0A3Q2C937_CYPVA        Unreviewed;      2818 AA.
AC   A0A3Q2C937;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Vacuolar protein sorting 13 homolog C {ECO:0000313|Ensembl:ENSCVAP00000001271.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000001271.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000001271.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the VPS13 family.
CC       {ECO:0000256|ARBA:ARBA00006545}.
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DR   STRING; 28743.ENSCVAP00000001271; -.
DR   Ensembl; ENSCVAT00000013698.1; ENSCVAP00000001271.1; ENSCVAG00000006832.1.
DR   GeneTree; ENSGT00950000183083; -.
DR   Proteomes; UP000265020; Unplaced.
DR   InterPro; IPR026847; VPS13.
DR   InterPro; IPR049424; VPS13_C.
DR   InterPro; IPR031645; VPS13_DH-like.
DR   InterPro; IPR031642; VPS13_mid_RBG.
DR   InterPro; IPR009543; VPS13_VAB.
DR   InterPro; IPR004170; WWE-dom.
DR   PANTHER; PTHR16166:SF125; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13C; 1.
DR   PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR   Pfam; PF21679; VPS13_C; 1.
DR   Pfam; PF16909; VPS13_DH-like; 1.
DR   Pfam; PF16910; VPS13_mid_rpt; 3.
DR   Pfam; PF06650; VPS13_VAB; 1.
DR   PROSITE; PS50918; WWE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          2183..2263
FT                   /note="WWE"
FT                   /evidence="ECO:0000259|PROSITE:PS50918"
FT   REGION          179..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..194
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2818 AA;  311640 MW;  6E50B387909CA798 CRC64;
     MERVCFRDAR SRKDVKHKKY KTLQTGLCLQ LHSVDQNSVT SSSSLEAIMD RAYERYDVGL
     RRVQLLYRDA WKSARLQSSS VQHILQPMDL TLHLAKCMVE KDARMPRFKV SGELPLMHVR
     ISDQKIQKVL ELVESVPVPK KDSAPCSPTE KVSSKRCSYG WTCWRRSCFR SGSPVLLPDS
     EEEAGDRLTN EEQHLSSKRS AGAPSGRLVL GNQPLTLQYV ASQVLLELTQ QADQEKAVLS
     FNISQLGAEG RMRSFDLSVA SYLRRLAVDY CDVPGDEPLH LISSLQQQDS NLLKVEFIKA
     DPNGPSFQTQ FSNTEQTLKV ELSSLDFLLH TKALLATISY LNSAVPQQFS ATRDPDTKKL
     VQKTEQSQTG RSPLFTLSKS KKDGGVFTFK LFATLGCFHV EVCDDRCSIA DIRVQGTNAP
     LSAASMFPPH RNQGLDARLC SQSVLVTEVT SSSSSPQAVS IVGNEVFSFK LSLFPGATQG
     EGYGDMSKVD GKVTMSLGCI QIVYLHKFFM SLLMFVDNFQ TAKEALSAAT SQAAERAASS
     VRDFAQKSFR LSMDIKLKAP IIIIPQSSTS QNALVVDLGL ITVGNSFALR PIETLPLPAV
     VEKMEVKLTQ LKLSRKTPKI DFPPKDIEIL QPINVDLLVT RNLAASQFSD IPGVQVQGVL
     RSLNMSLGEE ELGVLMKILV ENIGEGSKDQ NLEVKTQAST HQELSEKDVV KVLLGFEVKQ
     VLLSLKKRIK LEEAPFLVFQ LDQLGIDAKV RKYDLSATTY IRQVSMKSLE FKGQAAHGAG
     FCGFTGIYLS QSLSLQVTFS SLDVTLHTQA LLSAVNFLSS SLSSGSAAPA EKDIQLKTEE
     KTPSVKPSQY LSCRQNQRDT VIDLKATMTL GAFNILVCDQ TCSMADIKVK GLNSSFLMQG
     AQTHISARLE DVIVLDVDPK GIHKEAISIV GDEVFSFSMS LTPNATEGPG YTDTSRTDGR
     VKLSVGCIRV VYLHKFFMSL LNFSNNFQTA KEALSSATAQ AAEKAASSVR DLAQKSFRLS
     MAVRVKAPLI IIPQSSTSKN AIVVDLGLIT VENSFSLVTV AGCSLPAVVD SMDVQLSELK
     LSRSKPNIEL LKPVNLLLNI RRNLSAGWYR KMAAVEVNGD LKPMKVILSQ DDLRVMLRIV
     TENLGEANTL DPSAPQQEVS LRVQAPKGAP TGPTDSEEPW KPARLERLSL YLTLLLLFQS
     SQTHYGSSFQ QPADLQHHQD LRLGELALRL MKASGKILNN GSMEVNTVLT ACTLDDLRSG
     VDRVTSRMVG QKEDGQQAMI DVTFRQAPAE RDLVAILQKL YLCASTEFLM AVADFFLQAV
     PQSPASAPPA AATSAVRTRL RAVIVDPEVV FVANLMKADA PALVASFQGD FNLVAEEDGT
     QNMRANLRDL KVLACPFIQN KEDKSVTTVL KPCSVSMETK TSPNQPLSGF VTVEEVIIKI
     SPVILNTVMT ITAGIAAKTQ AEQSQEQKAD VSNLWSIMDI YNCNFWFLGV DQATEITENY
     AESDGTEGCS VSFPQSVQMT LESGLGHRTV PLLLAESSLN GVAKNWSSLL HLTADMTLEV
     RLSFRRAGHL RLINNSLVML WEILVIPEPE DLVRLANVAA VLLCLATVAF AEGTALTFDH
     TLKEKPPFTI KNSLGIPVIV QHSASLRPVG SVAQGKLHEL SVDQSMDLVH SGFESTMGGK
     LSALERQESF LLTIPVDKPG RRLYNVRGPM LQEAVSVLLQ IDAAEGNKII TVRSPLQIMN
     HFSEPFSILK YCAASRDLQS IGTAEPEKEF HVDLDAYRCQ LFVRPAGRLD GLYAASSSCM
     AWKEQVHCSA EVQSVLQCPA SDSNLLPLMV STLAVPDDLR HISSHGEEDW DPAYVIHLHP
     VAALCNLLPY TVSYIMENSA NVYELQEGTT SDLLNARLSG EIMSLALLQY QGRGWHGHIQ
     ITRELPEFFA VSLTCDTDAS LSVDVSIHVT KTKSRLLLSL FSPYWIINKT SRVLQYRSED
     VMYKHPAEYR DVVLFSFKKS NLFTKSKVSV SQRGGVSSGR GVFILDGDKI KCNDFYLSQL
     NNLLLSFCTS LMLLLFSNYC KNVHSCILVI YSPVLYYEVH ELKPCEARRF VWDDPGGTRK
     LCWSCKGRSE ELDLLKDDVG QFPFDGQSHV HWVSFLDGRQ RVLLFTEDTG VVTKARQSEE
     LEQFQQELKV SLQNLGLSLV DNSSRQEISY IGITSSGVVW EYKPKNRWKS FNQKNINLLE
     KTYQSQLSEK KELGWVTLEN NLEVNLNQAV MKMRQPQSCP VRRNFLSGIQ VEFKQSLHQR
     SLRAQLHWLQ VDNQLPGAVF PIVFHPVPPP KSIALDSEPK PFMDMSVIMR FNQHSSVMQF
     KYFMALVQEM AVKIDQGFLD AVAALFAPAA NLQNDGQKRL QAEPTDASLA DGSGISFFEF
     FHISPIKVTL SLGSSDGDSA QQNPITQSLN LVLKSIGATL TNVDDIIFKL AFFEVKYQFY
     SKEKLMWAVG RHYTEEFLKQ MYVLVLGLDV LGNPFGLIRG LSEGVEAFFY EPFQGAVQGP
     EEFAEGFAIG VRSLLGSTVG GAAGMFSKIT GSMGKGLAVI TMDKEFQQER REEMNRPTRD
     FKGSLAKGGK GLLKGVVGGV TGIVTKPVEG AKKEGAAGFF KGIGKGLVGV VARPTGGIVD
     MASSTFQGIQ RAAEATEEVT KLRPVRLIKE DGVIRPYDAT ESQGFDLYQR TGIKPLEGEA
     FRTHCPNPAH RKSNIIVTNR WVQLKAEMDL LGHLITDWEC LFENFHRPPA VSGSELKIYC
     KVTNTHCFQD SRDPFLTPPL SDPPQKLHEA IWDAQDAQKQ HHMVRQKSQR FLRLSKKQ
//