ID A0A3Q2C9S8_CYPVA Unreviewed; 1861 AA.
AC A0A3Q2C9S8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Tenascin-like {ECO:0000313|Ensembl:ENSCVAP00000001561.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000001561.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000001561.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- SIMILARITY: Belongs to the tenascin family.
CC {ECO:0000256|ARBA:ARBA00008673}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_015243026.1; XM_015387540.1.
DR Ensembl; ENSCVAT00000013206.1; ENSCVAP00000001561.1; ENSCVAG00000002557.1.
DR GeneID; 107092858; -.
DR CTD; 100149028; -.
DR GeneTree; ENSGT00940000155188; -.
DR OrthoDB; 5489847at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00063; FN3; 11.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR Gene3D; 2.10.25.10; Laminin; 13.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR041161; EGF_Tenascin.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR46708; TENASCIN; 1.
DR PANTHER; PTHR46708:SF1; TENASCIN; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF18720; EGF_Tenascin; 10.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF00041; fn3; 11.
DR SMART; SM00181; EGF; 14.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00060; FN3; 11.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 8.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50853; FN3; 9.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1861
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018528694"
FT DOMAIN 374..405
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 595..685
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 774..865
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 866..951
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 956..1044
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1096..1185
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1189..1280
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1370..1459
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1460..1546
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1547..1635
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1635..1850
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 903..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1061..1075
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 378..388
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 395..404
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1861 AA; 203068 MW; 4C879AF4FAF77B04 CRC64;
MGTHSLLGFL LLITLISLTN AGFVKKILRH KRQTLSPPSE HNVTFPSADH PVVFSHVYNI
NVPESSLCSV DLESPEGAHV HSKDIAAVPQ GHHVTEHTFN GENQILFTHR INIPRQACGC
KDDFPGLKEL MSRLEMLEGE VSALRDQCSS EQLTGELGTK PYCNGHGKYS TETCACICDP
GWRGPNCTEG ECPTSCQDRG RCVDGKCECY KGFTGEDCAL KTCPMDCGAH GICEREVCVC
SDGFFGEDCS ESRCLNNCLG RGRCDEGDCI CDEPWTGLDC SELICPNDCY DRGRCVNGTC
YCDEGFSGED CADFSCPNNC RGNGFCVDGK CICTVGYSGQ DCSQLTCLND CNDRGRCFNG
VCICDSGYQG EDCSQVACVN NCHNRGQCIN GRCSCDAGFH GDDCSELSCP NNCQLKGRCV
NGQCVCDEGF AGEDCSIHTC PSNCYGRGEC IEGRCACHVG YVGEDCSQLS CPNNCNNRGR
CIDGQCVCDE GFSGEDCSQK ACLNDCLARG YCIDGKCFCH EGYTGESCSI LACPENCNNR
GRCVNGRCTC DSGYEGESCA DLSCINNCQD KGRCVNGQCF CDEGYIGEDC SEVSPPKDLT
VGEVSTETVD LSWNNEMLVT EYLITYVPTS PGGLLMEFTV PGDKNAATVK ELEPGIEYLI
SVYAVLSNKR SIPVSARVAT DLPQPEGVRF KSVRETSVEV VWDQLDISFD SWEIYFRNTK
EENGKVVSTL PPSQNEFLQS GLGPGQEYEV SINVVKNNTR GPQTSRTVTT KIDGPRQVEV
KDVTDSSALI SWYLPVAPAD GVTIFYMPSS NHSDETTVDV SPSDKQYSID NLKPDTEYAV
SIISRHKEAT SDPVTTIFTT ELDAPTAAQA VSQTDDSITL EWTNSQADVS SYRVKYTPIS
GSSHGERVFP RGSGRTTQAT ITGLKPGTEY GVGVTAVKHE RESLPATTNA ATELDPPRDF
KQIRSTETSL SVSWQKPQAK LSGYRLEYMS RDGQAEQVDI PASANTFVLS DLIPGMSYTM
TLTAERGHKR SRPVSLTAST APPDVLALSI KEAPTTAISA QDEENHKHGY DISSEAPSDN
EEMISGAEPE SSGMELLSNL TPVNVTATSM SLVWSAPDEA FDSFLVELVA PSAAAAQPRV
TTIPGGLRKA KIEGLLPSTL YEITLHGLME GTPSLPLRVF TTTAGLEPTL GNLIISDITW
DSFVASWNPT GEDFNSFVIE VTNMDDLAEA QNLTLSGDAT SLLISGLNPN TSYMVGLYGT
HQGSFLEPLY SEATTEAEPE VEHLFISDIT SHSFRLSWAA DEDQFDRFVI KIRDSKRLAH
PREYKARGSE RTKVITGLMS GTEYEIELYG LTLDQRSQPI TAVAQTGLSA PKGLHFTEVT
DSSAVVHWSN PRSQVDSYRI TYVPFEGGSP LILNADGSMS EMLLINMFPG KTYQVTVSSL
KGLEESEPST GTVTTALDSP RGVTAVNVTD TSALLSWQPS VATVDGYVIT YSTDTVSPVV
EHVSGNIVEF QINTLVPGSH YTAAVYGVKE AQRSESTLTA FTTDLDPPRD LMANNVQTDT
ATLTWKPPTA AVTGYMLSFS SPGGVIREVM LSPTASSYSM SQLTGSTKYD VRLQAISGAQ
RSRYVTTTFS TNKVGQLYAR PWDCAQILLN GETTSGLYTI YIGGEESQPI QVYCDMTTDG
GGWMVFLRRQ NGKLEFFRNW KNYTAGFGNM NDEFWLGLSS LHKITSLGHY ELRVDLRDNE
ESAYAQYDKF TIAEPRTRYK VYLGAYSGTA GDSMSYHQGR PFSTYDNDND IAVTNCALSY
KGAFWYKNCH RVNLMGKYGD SSHSKGINWF HWKGHEHSIE FAEMKIRPAN FKNPESRKKS
S
//
