ID   A0A3Q2CDP2_CYPVA        Unreviewed;       775 AA.
AC   A0A3Q2CDP2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Mitogen-activated protein kinase 8 interacting protein 1 {ECO:0000313|Ensembl:ENSCVAP00000003083.1};
GN   Name=MAPK8IP1 {ECO:0000313|Ensembl:ENSCVAP00000003083.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000003083.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000003083.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the JIP scaffold family.
CC       {ECO:0000256|ARBA:ARBA00009866}.
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DR   RefSeq; XP_015244946.1; XM_015389460.1.
DR   AlphaFoldDB; A0A3Q2CDP2; -.
DR   STRING; 28743.ENSCVAP00000003083; -.
DR   Ensembl; ENSCVAT00000010635.1; ENSCVAP00000003083.1; ENSCVAG00000004240.1.
DR   GeneID; 107094058; -.
DR   KEGG; cvg:107094058; -.
DR   CTD; 9479; -.
DR   GeneTree; ENSGT00940000157089; -.
DR   OMA; GHHRERI; -.
DR   OrthoDB; 2904222at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046328; P:regulation of JNK cascade; IEA:InterPro.
DR   CDD; cd01212; PTB_JIP; 1.
DR   CDD; cd11943; SH3_JIP1; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR047178; JIP1_scaffold.
DR   InterPro; IPR035638; JIP1_SH3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR47437:SF3; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR47437; JNK-INTERACTING PROTEIN 1-LIKE PROTEIN; 1.
DR   Pfam; PF00640; PID; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   SMART; SM00462; PTB; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS01179; PID; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          554..615
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          631..764
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          483..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        197..230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..247
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..318
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  85919 MW;  1EFFA9B1B4CE3FD5 CRC64;
     MADREQRKAT PPPGRSVQVN SPASCRLTHD ISLDEFEDDD LSEITEITDE RGMSLNCNGP
     DIRGRVRRGT SSVSGRVELG AVGQLQAGML HLDLIDGADG YCGDKEASAV AIAPGIKDSG
     APVTMDTYRP KRPTTLNLFP IVPRSQDTLN NNSFGKKYSW QEKVSGSSSP LKTGDLTPPR
     EHSCLSDEDK VQGGAAQTKD RGTSTDAPCR HGHTSGHSHS SSSGAATCSK LQEKPPQPPP
     PQNYTPAPLY PAGKQDSLGH RDKTRYQTDV HLEPTEEIYL TPVQRSAESL EPPNVQDRPF
     LSQQTEQGRM SISSDTEGPP PYQPLPDRTN PSIFEEDELY LPPPSYASCV ESLITPPSTA
     ALDLSLKGTG AGAMLRPGSS VEYVDATDES YCGEDEDVDR IMMDGKMKKM EGKGDKPAPL
     RTTISSEASS LTYDSVKYTL VVDEHAQLEL VSLRQCYQGF SDDSDSATVY DNCVSSPYES
     AIGEEYEEED EDEDHDPRAG AAQREATACL SEDSTPEEDL HFTKKFLNVF MNGHSRSSSA
     ESFGLYSCII NGEEKDQTHR AVYRFVPRHD DELELEVDDP LLVEVQGEDY WYEGYNMRTG
     AHGIFPAYYA IEVNKDAECY KVKSSEWMDR YRLKFLGSVQ VPYHKGNDVL CAAMQKIANN
     RRMTVKFNPP SFCILEISVK GIKLAVQEDY YACNGSNECS HFFQLKNVSF CGYHPKNSKY
     FGFITKHPAD QRFACHVFVS ENSTKPIAES VGKAFQLYYK EFVEFSCPTE DIYLE
//