ID   A0A3Q2CFB0_CYPVA        Unreviewed;       663 AA.
AC   A0A3Q2CFB0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Phosphoinositide 3-kinase regulatory subunit 5 {ECO:0000256|ARBA:ARBA00040195};
GN   Name=PIK3R5 {ECO:0000313|Ensembl:ENSCVAP00000003652.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000003652.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000003652.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3Q2CFB0; -.
DR   STRING; 28743.ENSCVAP00000003652; -.
DR   Ensembl; ENSCVAT00000009671.1; ENSCVAP00000003652.1; ENSCVAG00000000146.1.
DR   GeneTree; ENSGT00530000063753; -.
DR   OMA; HELINDC; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005944; C:phosphatidylinositol 3-kinase complex, class IB; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:InterPro.
DR   InterPro; IPR019522; PIK3R5/6.
DR   PANTHER; PTHR15593; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR15593:SF2; PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5; 1.
DR   Pfam; PF10486; PI3K_1B_p101; 3.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
SQ   SEQUENCE   663 AA;  74492 MW;  360F762890E54F57 CRC64;
     MCSAGQSMNR WSLEELVKRD PENFLILLQQ IIRKTREAQE QCQYELVPPL AIMFTSTLLQ
     TPYCPPHSEL LEEALEVFYS FLTWPEPYCS VCRELLSMLQ LEIKAPGEHE GSSRRTRPLG
     ILQTLPLPTA KTYTFHWEKD NFGKICSLEK YDEESGAVDP ALIVANSCNS SHRVSTFSTI
     SSLSTTSKDS MYSTLSVASE SYPPSIYSGV DSDYFEDSDD YISSSPVAEK CSPKSSKVST
     RLSQHFHRLF IKPKNPRMLS RAKSLGNSES KDILVVRETR SNSLPQQVRL FSSDSLPRPQ
     IQALRHVCFR RRPILSSDED NKNTTLRVVV FGADHVAGKV ARAYSSLRKN ESACPRLTRA
     FNLQFYFVPV KRDPGSGHRR SSTPLVQTGS PKGSGLLLVS GSQLFSIWEI EIKKGESLIQ
     SKQSPKTLTY AEPSMYFYYF GRIRSLHPLT WELLMLACGE RRTEVFVHSL ELGHTAGTRA
     IKAMGEPGCS YKRFGIDGDR EAVPLTLDVV YNRVVVSGRS QWRRETKVCT SVNLIKACKN
     PEELDSKMEC LQLTMTEVLK RQNGKSKKGY NQVSYDVTSA QVKVDKVQVS GVGNTTFAVC
     LDQDEKKILQ SVTRCEISVC YKPDSSTDWR LRKSQASAQI QPLNPTFCSL LCLPIVTFSG
     ALP
//