ID A0A3Q2CK12_CYPVA Unreviewed; 549 AA.
AC A0A3Q2CK12;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25-like {ECO:0000313|Ensembl:ENSCVAP00000005552.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000005552.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000005552.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_015231298.1; XM_015375812.1.
DR AlphaFoldDB; A0A3Q2CK12; -.
DR STRING; 28743.ENSCVAP00000005552; -.
DR Ensembl; ENSCVAT00000006491.1; ENSCVAP00000005552.1; ENSCVAG00000006949.1.
DR GeneID; 107085483; -.
DR KEGG; cvg:107085483; -.
DR GeneTree; ENSGT00940000164979; -.
DR OMA; SKRVMAT; -.
DR OrthoDB; 5359093at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16597; RING-HC_TRIM25_C-IV; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF40; E3 UBIQUITIN_ISG15 LIGASE TRIM25; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 20..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 86..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..120
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 61785 MW; 8FD3A75612C7EAA4 CRC64;
MADLEDSGFS LMSLEDELTC SICLSTFDCP VTIPCGHNFC QDCLLSSWTD SYSCPQCRTP
FENKPELKKN TVLSTVVETF RVRATKGEGV QHVDEEEEDD DDDDYEEDED DDDDDDDDEE
EEKNVIRCDT CMEAEAAQTC LTCMASFCEE HLRPHRENPT FRLHQLTDPI EDLSEHICSD
HHKLMEHFCS NHGRLICSLC LQQVHKGCAF TSPEEQRSLK ESEFRDKLGI LDIKIDKTDN
IVLQMNELQG KLKDAANKKK MALAAVYQQI REMLAQDERV AQHEVDCELE AGQNKLGDLT
KKFNNNSERM KKAREEVYNL LSHAQTPAFL QASFELPKVV KFDPHPPRVN LDSKRVMATQ
SFATTLQESL TMLFSQPFEA RGPLLKPELN TGSDASGKAE ASLPRAENST SWTESQSYQP
PDQRPPPRSH SPGCPPIQTV YQPVHIPFYI QGKPTWNPKP GQSTGFTRPP FFPGQKPYKN
ADGSHKPHQN KKADGGHQPH HKQGKHPPSA QGGQKPGGKG PDSAKKDKPK SHPPSEKRAG
HNPHPRKNK
//
