ID   A0A3Q2CKS3_CYPVA        Unreviewed;      1122 AA.
AC   A0A3Q2CKS3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Myelin transcription factor 1 like {ECO:0000313|Ensembl:ENSCVAP00000005874.1};
GN   Name=MYT1L {ECO:0000313|Ensembl:ENSCVAP00000005874.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000005874.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000005874.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the MYT1 family.
CC       {ECO:0000256|ARBA:ARBA00010194}.
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DR   AlphaFoldDB; A0A3Q2CKS3; -.
DR   Ensembl; ENSCVAT00000005953.1; ENSCVAP00000005874.1; ENSCVAG00000007520.1.
DR   GeneTree; ENSGT00940000155671; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.320.30; -; 5.
DR   InterPro; IPR013681; Myelin_TF.
DR   InterPro; IPR002515; Znf_C2H2C.
DR   InterPro; IPR036060; Znf_C2H2C_sf.
DR   PANTHER; PTHR10816:SF11; MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN; 1.
DR   PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR   Pfam; PF08474; MYT1; 1.
DR   Pfam; PF01530; zf-C2HC; 5.
DR   SUPFAM; SSF103637; CCHHC domain; 5.
DR   PROSITE; PS51802; ZF_CCHHC; 5.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01143}.
FT   DOMAIN          565..811
FT                   /note="Myelin transcription factor 1"
FT                   /evidence="ECO:0000259|Pfam:PF08474"
FT   REGION          1..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          144..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1005..1067
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        18..61
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..123
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..171
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..243
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        611..625
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        630..656
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1122 AA;  123609 MW;  7E4FC3EED4A3A1E2 CRC64;
     TLETSPKRST YLDDMDNSTM EECYETDGTE EMDDREEDEE GAVEEEGEVE EEEEDVEGYM
     DYNVEQMEHE DRENEDRGEG EEEEEVEVEQ DEEEESEEVR VEEAEEEDDA IEEKDDNNND
     EYENYDELVA KSLLNLGKIA EDAANRAMTE SEMNSNSSHS EEGDDTQRED MSLDVDSDVV
     RETVDSLKLL AQGHGAVLSD SLDGQEFENG TSGNGDENNC SHSGGNAHNG GHLRTSSNGQ
     MENSDEEVCL SSLECLRNQC FDLARKLSET KPNERSGPSQ QNHYSCGDPN QQPQHHSYGD
     YHSSQNDRHT LDRNYSDMDN LMKLEEQLSP RSKAFSSCAH DERYHTNNHR DFDEDTASVT
     SDRSEEVFDM TKGNLSLLEK AIALESERAK AMRDKMAAEA ARRDGVRYTH EEHGPRHGYS
     VERKARLPDG MKKPFFHKDV SRADKKESRC PTPGCDGTGH VTGLYPHHRS LSGCPHKDRV
     PPEIVAMYEN VLKCPTPGCT GRGHVNSNRN SHRSLSGCPI AAAEKLAKAQ EKHQSCNGPK
     SNQASDRVLR PMCFVKQLDY PQYGYKNNVS TSTPRSNLAK ELEKYSKTSF DYSAFDGSNN
     HQVYGKRAIA PKVHGHRDTS PKGYDAKRYC KNSSSASSTT STYAPSSSNS SLSCGGGGGG
     TGGGGGGSSA AHMAATAILN LSTRCREMPH GLGGKPQDLC SQSPGLDVDE NGTLDLSMSK
     SLCGGGAGDS VLTPLEPMSP QRQAALLGSR CYGMGDAADC WDLPVDYTKI KHIDEDEKEP
     DDLDPFHDLL EDRSYTTDVN MPSPKPKYAQ CKESKKDLIT LSGCPLADKS IRSMLANNAQ
     ELKCPTPGCD GSGHITGNYA SHRSLSGCPR ARKSGIKIIH SKENKEDQEP IRCPVPGCDG
     QGHVTGKYAS HRSASGCPIA AKRQKDGYLN GIQFTWKSGK TEGMSCPTPG CDGSGHVSGS
     FLTHRSLSGC PRATSAMRKA RLSGVEMLTI KHQRASNGLE HDEEIKQLDD EIKDLSESNS
     QVEADMIKLR TQITTMETNL KSIEEENKVI EQQNESLLHE LANLSHSLIN SLANVQLPHM
     VRNFDAYVTT LTDIYTNQEQ YQSAENKALL ENIKQAVQGI QV
//