ID   A0A3Q2CNU7_CYPVA        Unreviewed;       796 AA.
AC   A0A3Q2CNU7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Nuclear cap binding protein subunit 1 {ECO:0000313|Ensembl:ENSCVAP00000007067.1};
GN   Name=NCBP1 {ECO:0000313|Ensembl:ENSCVAP00000007067.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000007067.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000007067.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NCBP1 family.
CC       {ECO:0000256|ARBA:ARBA00007413}.
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DR   RefSeq; XP_015226151.1; XM_015370665.1.
DR   AlphaFoldDB; A0A3Q2CNU7; -.
DR   SMR; A0A3Q2CNU7; -.
DR   Ensembl; ENSCVAT00000003925.1; ENSCVAP00000007067.1; ENSCVAG00000008795.1.
DR   GeneID; 107082143; -.
DR   KEGG; cvg:107082143; -.
DR   CTD; 4686; -.
DR   GeneTree; ENSGT00390000001733; -.
DR   OMA; CAAEGLM; -.
DR   OrthoDB; 5477544at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027159; CBP80.
DR   InterPro; IPR015172; MIF4G-like_typ-1.
DR   InterPro; IPR015174; MIF4G-like_typ-2.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR   PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   Pfam; PF09088; MIF4G_like; 1.
DR   Pfam; PF09090; MIF4G_like_2; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   3: Inferred from homology;
KW   mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Transport {ECO:0000256|ARBA:ARBA00022816}.
FT   DOMAIN          28..240
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          663..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        663..680
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        681..696
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   796 AA;  92656 MW;  AC939143F8A2DC7D CRC64;
     MSRRRHSDEN DGGQAHKRRR TSEPIEIEDR LESLICRVGE KSTSSLESNL EGLAGVLEAD
     LPNYKNKILR ILCSVARLLP EKLTVYTTLV GLLNARNYNF GGEFVEAMIR QLKETLKNNL
     YNEAVYLVRF LSDLVNCHVI AAPSMVVLFE NFVSVTQEED VPQVRSDWFV YVVLSCLPWV
     GKELYEKKDV EMDRLLGQIE GYLKRRVKTH VPMLQVWTAE KPHPQEEYLD CLWAQIQKLK
     KDRWQERHIL RPYIAFDSVL CEALQHNLPP FTPPGHMPDA QYPIPRVIFR MFDYTDAPEG
     PVMPGSHSVE RFVIEENLHC IMKTHWRERK TCAAQLLSYP GKNKIPLNYH IVEVIFGELF
     QLPMPPQIDV MYTTLLIELC KLQPGSLPQV LAQATEMLYM RLDTMNTTCI DRFINWFAHH
     LSNFQFRWSW DDWADCLTMD LDKPKPKFVK EVLEKSMRLS YHQRIVDIVP PTFSALIPAD
     PIFSFKYDDE SGSSLPGYPV SVLVSNAIKN RASNEEILTI LKEVPNPNQE EDDDEGETFN
     PLKIDVFLQT LLHLAAKSFS HSFSALGKFH EILKALTESD DGKLHILKVV YEVWRNHPQM
     IAVLVDKMIR TQIVDCAAVA NWLFSQDMAH EFTRLFIWEI LHSTIRKMNK HVQKIQKELE
     EAKEKLEKQQ HKRRDSGDDE DMEKNSEEDD EGQLEEQIER LQEKVESAQS EQKNLFLVIF
     QRFIMLLTEH LVRCETGSVD ISTPWYKNCI ERLQQVFLMH HGTIQQYMGT LENLLFTAEL
     DHHILAVYQQ FCALQL
//