ID A0A3Q2CPU8_CYPVA Unreviewed; 168 AA.
AC A0A3Q2CPU8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Endothelin-2-like {ECO:0000313|Ensembl:ENSCVAP00000007581.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000007581.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000007581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the endothelin/sarafotoxin family.
CC {ECO:0000256|ARBA:ARBA00010959}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_015251328.1; XM_015395842.1.
DR AlphaFoldDB; A0A3Q2CPU8; -.
DR STRING; 28743.ENSCVAP00000007581; -.
DR Ensembl; ENSCVAT00000003061.1; ENSCVAP00000007581.1; ENSCVAG00000009239.1.
DR GeneID; 107098270; -.
DR KEGG; cvg:107098270; -.
DR GeneTree; ENSGT00950000183053; -.
DR OMA; DRECIYF; -.
DR OrthoDB; 4317037at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR GO; GO:0042310; P:vasoconstriction; IEA:UniProtKB-KW.
DR InterPro; IPR020475; Endothelin.
DR InterPro; IPR019764; Endothelin_toxin_CS.
DR InterPro; IPR001928; Endothln-like_toxin.
DR PANTHER; PTHR13874; ENDOTHELIN; 1.
DR PANTHER; PTHR13874:SF9; ENDOTHELIN-2; 1.
DR Pfam; PF00322; Endothelin; 1.
DR PRINTS; PR00365; ENDOTHELIN.
DR SMART; SM00272; END; 2.
DR PROSITE; PS00270; ENDOTHELIN; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Vasoactive {ECO:0000256|ARBA:ARBA00022858};
KW Vasoconstrictor {ECO:0000256|ARBA:ARBA00023322}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..168
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018582762"
FT DOMAIN 46..67
FT /note="Endothelin-like toxin"
FT /evidence="ECO:0000259|SMART:SM00272"
FT DOMAIN 92..113
FT /note="Endothelin-like toxin"
FT /evidence="ECO:0000259|SMART:SM00272"
SQ SEQUENCE 168 AA; 19085 MW; 255D52BB6D1E79D4 CRC64;
MDSFLRKMLC LFIICMSLRD GCGLPLSDHL EAPVQAIHPH HIRTKRCSCN NWEDRECIYF
CHLDIIWVNT PSKLLPHGLG SSVSRRRRST KRCECRDPAD KTCNRFCRKS LEDSTTDILE
SPQKATATKS HILLSSLRSV LQSNMVIAKA VHSSNMKSSG ATETKNRR
//
