ID A0A3Q2CPX0_CYPVA Unreviewed; 476 AA.
AC A0A3Q2CPX0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Milk fat globule-EGF factor 8 protein {ECO:0000313|Ensembl:ENSCVAP00000007508.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000007508.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000007508.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_015242012.1; XM_015386526.1.
DR AlphaFoldDB; A0A3Q2CPX0; -.
DR STRING; 28743.ENSCVAP00000007508; -.
DR Ensembl; ENSCVAT00000003177.1; ENSCVAP00000007508.1; ENSCVAG00000009176.1.
DR GeneID; 107092199; -.
DR CTD; 558580; -.
DR GeneTree; ENSGT00940000156049; -.
DR OrthoDB; 3043281at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR46806:SF10; EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 PRECURSOR; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01285; FA58C_1; 2.
DR PROSITE; PS01286; FA58C_2; 2.
DR PROSITE; PS50022; FA58C_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..476
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018577075"
FT DOMAIN 20..57
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 60..104
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 117..153
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 156..312
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 317..474
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 47..56
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 94..103
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 143..152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 476 AA; 52438 MW; DAED4B29FDCE20DF CRC64;
MAPLFLWVLL LSGGLLFGAK GDLCPVNVCE NGGTCVTGTG TPFMCICPDG FSGDTCNETE
TGPCSPNPCE NDGVCEVTGQ SRRGDVFTEY ICKCQPGFEG VHCQTSVLGA NLSSAKDVND
CAAQPCENGG TCRDLEGDFK CHCPSPYVGK QCQQRCISLL GMEGGGIAES QIRASSVRYT
VLGLQRWGPE LARLHNKGLV NAWSSAAHDK NPWIEINVKR KMRFTGIVTQ GASRIGTAEF
IKAFKVASSM DGKTYTMYRT EGQSRDQLFV GNVDNDGTKT NLFDPPIIAQ YIRIIPVLCR
RACTLRMELV GCELDGCSEP MGMKSRLLSD RQITASSTFR TWGLEAFKWL PHYARLDKQG
KTNAWSPATN SRSQWLQVDL LSPKKITGII TQGAKDFGSV QFVSSFKVAY SNDGRSWTIL
KDGTTGKDKI FPGNSDNNVH KRNMFEPAVY SRYVRVLPWE WHQRITLRME LLGCDE
//
