ID A0A3Q2CQD6_CYPVA Unreviewed; 799 AA.
AC A0A3Q2CQD6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=CCR4-NOT transcription complex subunit 4 {ECO:0000313|Ensembl:ENSCVAP00000007692.1};
GN Name=CNOT4 {ECO:0000313|Ensembl:ENSCVAP00000007692.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000007692.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000007692.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_015246509.1; XM_015391023.1.
DR RefSeq; XP_015246510.1; XM_015391024.1.
DR AlphaFoldDB; A0A3Q2CQD6; -.
DR STRING; 28743.ENSCVAP00000007692; -.
DR Ensembl; ENSCVAT00000002871.1; ENSCVAP00000007692.1; ENSCVAG00000009399.1.
DR GeneID; 107095056; -.
DR KEGG; cvg:107095056; -.
DR CTD; 569055; -.
DR GeneTree; ENSGT00390000000068; -.
DR OMA; LHHRPMF; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 14..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 109..193
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 190..217
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 190..217
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 255..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 68..98
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 257..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..768
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 86458 MW; 0C12B8674B1B1876 CRC64;
MSHSPEMKDD PMECPLCMEP LEIDDVNFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
PEDPAVYKPL SQEEIQRIKN EKKQKQNEKK QKVTENRKHL ASVRVVQRNL VFVVGLSQRL
ADPEVLKRPE YFGRFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
VDGRTLKASL GTTKYCSYFL KSMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
LQDLYKLNPG FLQPPACATE KSNSKPNSTQ RTNSSNGKDG WPTLSGHNKL ANGLSEDRKS
PPLLDYPDQE ASNSDGLESE LGPGQRPTLS PFSSNCESNS SPNDKPPESV GLVNGETLQQ
MPTSDSPSPP PGLTKPILVV PISMSDHLAR SPFEGAAAES QSLFSDNSNF RHPNPLPAGL
PPFPSSPRGS SDWPMTPEPQ ILFTSDTIPV SSSTDWQAAF GFGSSSKQQD DDLGFDPFDV
TRKALADLIE KELSVQDQSP TSPGPLQQGS AGHSSGLPSS NSSTSHHFPS GLPRVHQFHH
RAIYSSFSFP GGHNSQAGQQ QPPAARHPWM GIPTRNTLAH LNHSASAASH SNILDLNLPP
QHNTGLGGIP MSENSSSIDG LNVKEWQDGL RALLPNININ FGGLPNSSSS SSSSSSNSVN
HIGGPAGPAG ISHSLSWDGT ASWMDPAIIT GIPSSPGNSL DCLQDDNPPH WLKSLQALTE
MDGPASSAVP TPQPLNSGLL DGHLPLHHRA PSGWAPYLPP PTGNPTAQFH SPPPGFQTAF
RPPGQPATEL LQSAAVDRH
//
