ID A0A3Q2CU61_CYPVA Unreviewed; 611 AA.
AC A0A3Q2CU61;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Kelch-like protein 21 {ECO:0000256|ARBA:ARBA00023877};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000009204.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000009204.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
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DR RefSeq; XP_015228608.1; XM_015373122.1.
DR RefSeq; XP_015228609.1; XM_015373123.1.
DR RefSeq; XP_015228610.1; XM_015373124.1.
DR AlphaFoldDB; A0A3Q2CU61; -.
DR STRING; 28743.ENSCVAP00000009204; -.
DR Ensembl; ENSCVAT00000000335.1; ENSCVAP00000009204.1; ENSCVAG00000011125.1.
DR GeneID; 107083703; -.
DR KEGG; cvg:107083703; -.
DR CTD; 9903; -.
DR GeneTree; ENSGT00940000158631; -.
DR OMA; TWSVVGQ; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18460; BACK_KLHL21; 1.
DR CDD; cd18250; BTB_POZ_KLHL21; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030577; BTB/POZ_KLHL21.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047069; KLHL21_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF255; KELCH-LIKE PROTEIN 21; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 38..105
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 611 AA; 69530 MW; D11236DD44B1209B CRC64;
MEKPVLQTQP SILPFFDSSH AFNLLRGIHE LRAERKFFDV TLCAEGREFH CHRTVLAAAS
TYFRAMFTGT LKESVMDRVV LHEVSAELLG LLVDFCYTGR VTVTQENVDL LLKTADLFQF
PSVKEACCAF LEQRLDVSNC LEIQDFAEAY ACRELAASAR RFVLKNIMEL AKGTDFERLP
WKRLLEFVSD DELCVDKEET VYQIAVRWVK TDLQRRLHYW PELLQQVRLP FVRRFFLLAH
VESDPLVYLS PTCLRMVNEA RSFQSCEYDR HDRPCHRMRP RPSTGLAEIL VVIGGCDQDC
DELVTVDCYN PQTGQWRYLA EFPDHLGGGY SIAALGNDIY VTGGSDGSRL YDGVWRYKSS
VNEWTEVSPM LKAREYHSSC VLKGQLYVVA SDSTERYDQA LDCWEALPGM LHPMDNCATT
ACNGRLYAIG CLTSEDTMAI QSYDPDTNRW TLVNCGQLPP WAFTPKTVTL NGLIYFVRDD
SADVDVYNPQ KNEWDEIRPM NQVHVGGSAA VLGGKLFVSG GYDDTFELSD VVEAYDPAIR
TWTVAGRLPQ KTFWHGSVSI FRQFMPLVAS TFGPIDVPES NAIHLHRHQR HQALHNLNNN
LNQNQDVNPA H
//
