ID   A0A3Q2CUM4_CYPVA        Unreviewed;       343 AA.
AC   A0A3Q2CUM4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Ubiquitin specific peptidase 53b {ECO:0000313|Ensembl:ENSCVAP00000009496.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000009496.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000009496.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C19 family.
CC       {ECO:0000256|ARBA:ARBA00009085}.
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DR   AlphaFoldDB; A0A3Q2CUM4; -.
DR   Ensembl; ENSCVAT00000015921.1; ENSCVAP00000009496.1; ENSCVAG00000011471.1.
DR   GeneTree; ENSGT00940000156337; -.
DR   OMA; HTHICDP; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   CDD; cd02257; Peptidase_C19; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR22975:SF39; INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 ISOFORM X1; 1.
DR   PANTHER; PTHR22975; UBIQUITIN SPECIFIC PROTEINASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          30..342
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
SQ   SEQUENCE   343 AA;  39043 MW;  47546031CAA8F4ED CRC64;
     MAWVKKFKKT GGGLKKSYQP GSMVSLALTK GLLNEPGQNS CFLNSAVQVL WQLDIFRRSL
     RQLSGHFCLG DACIFCALKS IFNQFQQSRE RVLPSDSLRN ALAETFKNEQ RFQLGLMDDA
     AECFENILER IHLHIVSDTA TDSCSSKSCI THQKFAMMLY EQFVCRCCGA SSDPHPFTEF
     VHYVSTTALC QQVDRTLGKN ERLRSDMFGE LLQAANSTGD LRSCPSDCGQ SIKIRRVLMN
     CPEIVTIGFV WDAEQSDLTD DVIRFLGPRL NLCGLFNRVT DENAKRSELH LVGMICFSSK
     HYSAFAYHTK SSKWMFFDDA TVKEVRIFAV KKRYLLLFYH FVM
//