ID   A0A3Q2CY94_CYPVA        Unreviewed;      1138 AA.
AC   A0A3Q2CY94;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=RIMS-binding protein 2-like {ECO:0000313|Ensembl:ENSCVAP00000010814.1};
GN   Name=RIMBP2 {ECO:0000313|Ensembl:ENSCVAP00000010814.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000010814.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000010814.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RIMBP family.
CC       {ECO:0000256|ARBA:ARBA00010749}.
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DR   AlphaFoldDB; A0A3Q2CY94; -.
DR   Ensembl; ENSCVAT00000017624.1; ENSCVAP00000010814.1; ENSCVAG00000013107.1.
DR   GeneTree; ENSGT00950000183203; -.
DR   Proteomes; UP000265020; Unplaced.
DR   CDD; cd00063; FN3; 2.
DR   CDD; cd12014; SH3_RIM-BP_1; 1.
DR   CDD; cd12012; SH3_RIM-BP_2; 1.
DR   CDD; cd12013; SH3_RIM-BP_3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR035753; RIM-BP_SH3_2.
DR   InterPro; IPR035755; RIM-BP_SH3_3.
DR   InterPro; IPR040325; RIMBP1/2/3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR14234; RIM BINDING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14234:SF18; RIMS-BINDING PROTEIN 2; 1.
DR   Pfam; PF07653; SH3_2; 2.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00060; FN3; 3.
DR   SMART; SM00326; SH3; 3.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          137..204
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          914..982
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          1039..1106
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          560..656
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          756..782
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..821
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          837..910
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1018..1038
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1116..1138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        610..629
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        689..722
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        848..864
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        889..910
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1138 AA;  126921 MW;  8ED4AC74BBF22D41 CRC64;
     MQAKVRELEE KCRSQSEQFN LLSKELEKFR LQAGKFDILS SEPINLSESP GSPNKSLSQL
     LNGLAAPTEK GNEGPTSRSL ISEFIRPLQI SGDKPELLSV KPTFLSRSRA SSPARAFLSE
     MDKELSSTTR SKPRFTGKVR LCVARYSYNP YDGPNEHPEA ELPLVAGKYL YVYGTMDEDG
     FYEGELLDGQ RGLVPSNFVE FVQDDETPSV QRRDTTVKES GYLNHSSLGP QRLLSGSTGT
     GTSISSLLSD SKLDCLSASS LGMDLLGSSS NGTGTLDVSI DEVGEDIVPY PRRINLIKQL
     AKSVIIGWDP PVVPPGWGSI SGYNVLVDKE VRMSVPYGGR TKSLIEKLNL ATNTYRISVQ
     SITDRGPSDE LRCTLLVGKD VVVAPYYLRV DSITQSSAEL SWMPSNSNYS HTIFLNGAEY
     DMVKAGGYRY KFFNLKSMTV YKVKVVAQPH QVPWQLPGDQ REKREISVEF CTQPAGPPLP
     PQEVQVQCGQ TPGVLQVKWK PPPLTPSGTS NGASVIGYAV CTKGQKIAEV LYPTADYVSV
     DLNRIQGLEA REVIVRTLST QGESQDSPVA MIPHNLLGSP RLSHRVTAPP PSIPHPVPQP
     HQVHSQTHPP YPSTYPPNHP QPQVQPLPRA QPHTLPHAQP HSQPVCQPPH PQLHFQRHSI
     PKSKPLISAR EPETKEHEVG LRLAQPWERS PSPLPPMHGP NLEPPLFPPR RSPSPQRILP
     QPQGVPIPNT IAKAMAREAA QRAFAEANRV DKRNIFSDRG NALPPLNSDE EEDGYDSPHA
     RRRGASVDEF LRGSELGRQH HHHHYSHSEE YHTESSRGSD LSDIMEEDEE DLYSEMQLEE
     GRRRSINSHS TLKIIGNSPS HGSPDRQDHS GRRPVHIGTP PQRRPIPSID GYDGRRHGRG
     RQSPDYFEES ESDDLTRVFV ALFDYDPLSM SPNPDAADEE LPFKEGQVIK VFGNKDTDGF
     YRAEIRGRVG LIPCNMVSEI QTEDDEMMDQ LLKQGFLPLN TPVEKLVNCD RFKDGRSINR
     RSRKSKRERN RRSGRQYPMS TRRMVALYDY DPRESSPNVD VETELTFCAG DVIAVFGEID
     EDGFYYGELN GHKGLVPSNF LEEVPDDVDV FLTDSPSRYP QDTPARIKTK RVHAPSQY
//