ID A0A3Q2CYT4_CYPVA Unreviewed; 439 AA.
AC A0A3Q2CYT4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Vitronectin-like {ECO:0000313|Ensembl:ENSCVAP00000011087.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000011087.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000011087.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_015229402.1; XM_015373916.1.
DR AlphaFoldDB; A0A3Q2CYT4; -.
DR STRING; 28743.ENSCVAP00000011087; -.
DR Ensembl; ENSCVAT00000017972.1; ENSCVAP00000011087.1; ENSCVAG00000013317.1.
DR GeneID; 107084203; -.
DR KEGG; cvg:107084203; -.
DR CTD; 403026; -.
DR GeneTree; ENSGT00530000063751; -.
DR OMA; FGAEESC; -.
DR OrthoDB; 5310951at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00094; HX; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 2.110.10.10; Hemopexin-like domain; 2.
DR InterPro; IPR000585; Hemopexin-like_dom.
DR InterPro; IPR036375; Hemopexin-like_dom_sf.
DR InterPro; IPR018487; Hemopexin-like_repeat.
DR InterPro; IPR018486; Hemopexin_CS.
DR InterPro; IPR020436; SMB_chordata.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR22917; HEMOPEXIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22917:SF3; VITRONECTIN; 1.
DR Pfam; PF00045; Hemopexin; 3.
DR Pfam; PF01033; Somatomedin_B; 1.
DR PRINTS; PR00022; SOMATOMEDINB.
DR SMART; SM00120; HX; 4.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF50923; Hemopexin-like domain; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS00024; HEMOPEXIN; 1.
DR PROSITE; PS51642; HEMOPEXIN_2; 4.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..439
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018608388"
FT DOMAIN 20..62
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT REPEAT 114..158
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 159..206
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 207..267
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 370..425
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REGION 314..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..346
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 50161 MW; E40239E4DFAA9F95 CRC64;
MKPAMVLLGL VLLLDTIFGA EESCLGRCGS FSPLNKCQCD SMCVYYTSCC QDFSTICPKK
VSRGDTFGEA EDMTDPTPNL NTVTPTLPSS LTPPPNTTHG YAPTVDPNAE PCSGRPFDAF
LQLKNGSIYA FRGEYFFELD DKSILPGYPK LIEDVWGIPG PISAAFTRIN CQGKSYIFKG
NQYWRFEGDV LDEDYPRDIS VGFEGIPSHL DAAFAVPAPS HRGKEKAYFF KGQKYYQYEF
KHQPSHEECV YMSRTSPSVL FTRYTDLFCD QPLESLLTDL FANLYTHDTS SRLIMRDWRG
ITPPVDAALV GKVSFNPKPT MSSPAARRRS RGRKRRPSRR RGPQRRRQSR YVFDDMWFYD
DLFDFGLDYS DMAEEVTVQD YKGTPVQNVY FFKKDKYYRV SLQTKRVDIV SPPYPRSIAK
YWLGCEEKPP SDTPRAEKR
//
