ID A0A3Q2CZD1_CYPVA Unreviewed; 544 AA.
AC A0A3Q2CZD1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Copine 2 {ECO:0000313|Ensembl:ENSCVAP00000011259.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000011259.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000011259.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the copine family.
CC {ECO:0000256|ARBA:ARBA00009048}.
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DR AlphaFoldDB; A0A3Q2CZD1; -.
DR Ensembl; ENSCVAT00000018184.1; ENSCVAP00000011259.1; ENSCVAG00000013562.1.
DR GeneTree; ENSGT00940000157653; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
DR CDD; cd04048; C2A_Copine; 1.
DR CDD; cd04047; C2B_Copine; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037768; C2B_Copine.
DR InterPro; IPR045052; Copine.
DR InterPro; IPR010734; Copine_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10857; COPINE; 1.
DR PANTHER; PTHR10857:SF3; COPINE-2; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF07002; Copine; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50004; C2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 8..130
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 137..262
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 544 AA; 60549 MW; EC15ECAEE56210E3 CRC64;
MAYTLGMAPD GRTRSVGPQH CVTRVELSVT ASNLLDRDVA SKSDPFCVLF HEVDGNWVEL
GRTETAVNNL NPVFGVKFQV DYHFEEIQKL RFAMFDEDKC ATQLYEHDFL GEFICTLGVI
VSNKKLHKPL ILANGKPAGK GSITITAQEL SDNRIITLTL SGRKLDKKDF FGKSDPYLEF
HKQGEDGKWM LVHRTEVIKN TLDPAWKPFT VPLVSLCNGD VDRSIKVLCY DYDNDGGHDF
IGEFQTTVSK MSEAQNSVEV EFDCINPKKQ KKKKNYKNSG VIIVKSCKIA HDYTFLDYIL
GGCQLMFTVG IDFTASNGNP REPSSLHYIN PLGSNEYLSA ILAVGQIIQD YDTDKMFPAL
GFGAQLPPDW KVHTLLFALC LSTFSGVEGI AQAYSACLPL IRFYGPTNFA PIINHVARFA
AQALQQEKAA QYFTLLIITD GVISDMDETR HAIVQASKLP MSIIIIGVGN ADFAAMEFLD
GDASVLRSNT GEEAIRDIVQ FVPFRDFRNA PKETLAKSVL AELPQQVTQY FKQRNVPPIN
PAPE
//
