ID A0A3Q2CZX0_CYPVA Unreviewed; 1216 AA.
AC A0A3Q2CZX0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cell division cycle and apoptosis regulator 1 {ECO:0000313|Ensembl:ENSCVAP00000011661.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000011661.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000011661.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2CZX0; -.
DR Ensembl; ENSCVAT00000018709.1; ENSCVAP00000011661.1; ENSCVAG00000014095.1.
DR GeneTree; ENSGT00530000063672; -.
DR OMA; LRYSDMH; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR045354; BURAN.
DR InterPro; IPR025224; CCAR1/CCAR2.
DR InterPro; IPR025954; DBC1/CARP1_inactive_NUDIX_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR045353; LAIKA.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR025223; S1-like_RNA-bd_dom.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR14304; CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN; 1.
DR PANTHER; PTHR14304:SF14; CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1; 1.
DR Pfam; PF19257; BURAN; 1.
DR Pfam; PF14443; DBC1; 1.
DR Pfam; PF19256; LAIKA; 1.
DR Pfam; PF14444; S1-like; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM01122; DBC1; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 699..733
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1193..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1094..1163
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 129..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..921
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..954
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..978
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1200..1216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 138898 MW; DC45D352AC3F5254 CRC64;
MAQFGGQKNP PWANQFAATS VSQPGHSGQS LDLNSLHSLG VQQQSLLGAS PSVYSQQSAL
AAASLSNQSA ANYQLSQQTA ALQQQAAAAA AAALQQSQIN SALQQYQQQQ QPPQQPPQQL
YNVPHQPPVA LPTSLSLSNP QQTAQITVSY PTPRSSHQQQ TQPQKQRVFT GVVNKLHDTF
GFVDEDVFFQ LSAVKGKTPQ VGDRVLVEAV YNPNMPFKWN AQRIQTLPQL GNQSHQQQPP
PLPQASPQIG SLYSEPGMQL RYTDMHSAMD NRQNSQAQAS NMMKSAPNML QSLPPPTTFS
VQAQNPSSLL QAQLSAVSLA PLLQNPPQPL LPQPPTKDVF GGGLLQPPVR IMQQAQNLRR
MEPTRFTTRN DRMPELILRP KEERRDRERD RRRSRERSPT RKRSRDRSPR RERSPRRNRK
AVPRYTVQFS KFSLDGSSCD LMELRRRYQS LYIPSDFFNA VFTWVDAFPV TRPFQFSNAC
NFHVLHKEVD PPVKNTAVLD PPDVSRAYSA KVMLLANPSL EELYHKSCAL AEDPQEVRES
FQHPARLIKF LVGMRGKDEA MAIGGHWSPS LDGADPEKDP SVLIKTAIRC CRALTGIDLS
LCTQWYRFAE IRYHRPEETH KGRTVPAHVE TVVLFLPDVW HCLPTRSEWE VLSRRLREQL
AEKLSAERKE ADGEQEEEEK DDEESKDDCV PTHWTKLDPK SMKVNDLRKE LDCRSLSSKG
LKSQLIARLT KQLKVEEQVE ESKEPEKTET KVAEEEEPPR TEDDKEDDEK RKQEEVERQR
RERRYILPDE PTILVYPNWA AKSGKFDCSV MSLSVLLDYR LEDNKEHSFE VSLFAELFNE
MLQRDFGYRI YKALASLPSK DEKKEKKAKK EGEKKEAEKR EIKKEKEEES EEPAAKKNKD
EEEEKRKCED KVIKMESRDE EEDEGSTANA EEYDPMEAED DDDDDDEDDD DDEDYKDRSD
RKDDHKSSKD RSSKDKKQMV TQNRDLLMAF VYFDQSHWGY LLEKDLEDIL YTLGLHLSRA
QVKKLLNKPV VREACYYRKL TDREKDEAAL SYNEAQIENL TGNRALLPIV KPCASSEPSE
SGNLIVYNGA MVDIGSMMQK LEKSEKSREE IEQKLITQEA KMGEDAKLKA QLEEANKVLT
KELEEVTSTL SRTEHTLRAV TEQKTIYYDY MRKSANTLMT TVNELLDVLK KEQVGEPSMK
TKSDEIQTSQ TNGADE
//
