ID A0A3Q2D020_CYPVA Unreviewed; 602 AA.
AC A0A3Q2D020;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=EWS RNA binding protein 1 {ECO:0000313|Ensembl:ENSCVAP00000011547.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000011547.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000011547.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RRM TET family.
CC {ECO:0000256|ARBA:ARBA00008448}.
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DR RefSeq; XP_015257134.1; XM_015401648.1.
DR AlphaFoldDB; A0A3Q2D020; -.
DR STRING; 28743.ENSCVAP00000011547; -.
DR Ensembl; ENSCVAT00000018548.1; ENSCVAP00000011547.1; ENSCVAG00000013836.1.
DR GeneID; 107102369; -.
DR CTD; 322880; -.
DR GeneTree; ENSGT00940000154191; -.
DR OMA; QSTAHGY; -.
DR OrthoDB; 162112at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034870; TET_fam.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR23238; RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR23238:SF3; RNA-BINDING PROTEIN EWS; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 322..408
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 463..494
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 1..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 62612 MW; 0ADF97E927B72E0D CRC64;
MASAPDYSSY NQSGAQQGYA SYAAQPSQTY GQSAQQGYGQ QNYGSYTQPA AAAADSSYTQ
TTPAAGAYPQ QQTQYGSTYG QQPAAGYPPA QSTAHGYTQS AQGYGASGYE STPAAAAAAA
PAASQSYGSQ PGYTAQSAYP GYGQQAAPSA PQSANSQPAA GYNQSSYSQA TSYGQQQPGY
QGQQAGYNQQ QGYQQQTPQQ QQAPPAYPPQ GAGSYGQPAA NQYNQQGGPP GYNQSGPYNN
YRQDGQGGGS GYPGAEPGRY PGGGDNRGRD GFDRGGMMHR GRGMGRGMGA GDRGGFSKPG
GPMGGDDREM GRPEEQDDSE NSTIYITGLT EKANIEEMAE FFKHVGPIRM NRRLGQPAIN
IYTDKDSGKP KGDATLSYEE PICAKAAVEH FDGKEFQGRR LKVSMARRKP MMGGMRGGMP
MRDGMMGRGG MMGRGGDRGG FGPRGGPRGM GRGGPTGGNM QQRAGDWECP NPGCGNQNFA
WRMECNQCKA PKPEGLGGGP PFPPGGDRGR GGPGMRGGRG MDRGGPAGVG GPGGPGGFRG
GWGGDRGGFR GRGGMDRGGF RGAGRGGPPM DRMGGRGGRG MGPPGGKMDM RDHRQERRDR
PY
//
