ID   A0A3Q2D0K5_CYPVA        Unreviewed;       573 AA.
AC   A0A3Q2D0K5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Actin binding LIM protein family, member 3 {ECO:0000313|Ensembl:ENSCVAP00000011931.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000011931.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000011931.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A3Q2D0K5; -.
DR   STRING; 28743.ENSCVAP00000011931; -.
DR   Ensembl; ENSCVAT00000019050.1; ENSCVAP00000011931.1; ENSCVAG00000014437.1.
DR   GeneTree; ENSGT00950000182850; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   CDD; cd09327; LIM1_abLIM; 1.
DR   CDD; cd09328; LIM2_abLIM; 1.
DR   CDD; cd09329; LIM3_abLIM; 1.
DR   CDD; cd09330; LIM4_abLIM; 1.
DR   Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR   Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR   InterPro; IPR032402; AbLIM_anchor.
DR   InterPro; IPR003128; Villin_headpiece.
DR   InterPro; IPR036886; Villin_headpiece_dom_sf.
DR   InterPro; IPR001781; Znf_LIM.
DR   PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR   PANTHER; PTHR24213:SF0; ACTIN-BINDING LIM PROTEIN 3; 1.
DR   Pfam; PF16182; AbLIM_anchor; 2.
DR   Pfam; PF00412; LIM; 4.
DR   Pfam; PF02209; VHP; 1.
DR   SMART; SM00132; LIM; 4.
DR   SMART; SM00153; VHP; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR   SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR   PROSITE; PS51089; HP; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW   ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT   DOMAIN          19..78
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          79..138
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          147..206
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          505..573
FT                   /note="HP"
FT                   /evidence="ECO:0000259|PROSITE:PS51089"
FT   REGION          330..361
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          435..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  64655 MW;  127F61AC076FA052 CRC64;
     AAALSGSQMS SSSRGNSPIM CERCREACHG EVVRVKNTHF HIHCFTCQVC GCDLVRSGFF
     HHSGEYICTE DYQRLYGTQC DSCDEYITGE VVSAMGRTYH PHCFVCSVCR RPFPIGDRVT
     FCGKKCVCQQ CSRSLKKDKP VKILGPSYCA GCSQEIKQGQ SLLALERQWH ITCFKCRTCG
     CTLTGEYISK DGIPYCEDDY HAQFGIKCEG CSRYISGRVL EAGGRHYHPS CARCARCHMT
     FQEGEEMYLT GSEVWHPMCK EAARLERKLR VSDTQSISNL LPFLSISLLH ILLVKMCCSC
     FLSLGGSFDF IMNVELRKRL SCSSAFTESP AHSHHGGSPL HYYHHGSESG RSSPYYTQPE
     PRCATPTTST FQVPKHFHVP AFSLPLTCHI IYPSFPLPPP VSRVRRFSSG GEEDGWNQNI
     NKGIGRMILK EEMKARSGVQ GNNHWRSARS SRSNSKETLN NLEYSSLNDS YISKSASLPG
     YGRNGPNRVS SPGFCGLFSY FHFMSVSFKI YPYEALVVSV RGEQHLPNDV DRARLERHLS
     PEEFYRVFGM SMSAFDRLAQ WKKNELKKQV RLF
//