ID A0A3Q2D1N7_CYPVA Unreviewed; 345 AA.
AC A0A3Q2D1N7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=COP9 signalosome complex subunit 3 {ECO:0000256|ARBA:ARBA00014878};
GN Name=COPS3 {ECO:0000313|Ensembl:ENSCVAP00000012172.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000012172.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000012172.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN3 family.
CC {ECO:0000256|ARBA:ARBA00007084}.
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DR AlphaFoldDB; A0A3Q2D1N7; -.
DR Ensembl; ENSCVAT00000019355.1; ENSCVAP00000012172.1; ENSCVAG00000014610.1.
DR GeneTree; ENSGT00940000153653; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR048621; CSN3_C.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR10758:SF1; COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR Pfam; PF21215; CSN3-like_C; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Signalosome {ECO:0000256|ARBA:ARBA00022790}.
FT DOMAIN 215..305
FT /note="PCI"
FT /evidence="ECO:0000259|SMART:SM00088"
FT REGION 324..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 39106 MW; E0C3F4BB96E9A8B5 CRC64;
MTQLCELINK SGELLAKNLS HLDTVLGALD IQEHSLGVLA VLFVKFSMPN IPDFETLFSQ
VQLFISTCNG EHIRYATDTF AGLCHQLTNA LVERKQPLRG VVILKQAIDK MQMNTNQLTS
VHADLCQLCL LAKCFKPALP FLEVDMMDIC KENGAYDAKH FLCYYYYGGM IYTGLKNFER
ALYFYEQAIT TPAMAVSHIM LEAYKKYIVV SLILHGKVQQ LPKYTSQIVG RFIKTFLTLS
LQDMASRVQL SGPQEAEKYV LHMIEDGEIY ASINQKDGMV CFHDNPEKYN NPAMLHKIDQ
EMLKCIELDE KLKSMDQEIT VNPQFVQKSM GSQDDDVGSK TSSYS
//
