ID A0A3Q2D3F0_CYPVA Unreviewed; 384 AA.
AC A0A3Q2D3F0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=NIPA like domain containing 3 {ECO:0000313|Ensembl:ENSCVAP00000012968.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000012968.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000012968.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NIPA family.
CC {ECO:0000256|ARBA:ARBA00007230}.
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DR RefSeq; XP_015235466.1; XM_015379980.1.
DR AlphaFoldDB; A0A3Q2D3F0; -.
DR STRING; 28743.ENSCVAP00000012968; -.
DR Ensembl; ENSCVAT00000020357.1; ENSCVAP00000012968.1; ENSCVAG00000015421.1.
DR GeneID; 107088051; -.
DR KEGG; cvg:107088051; -.
DR CTD; 57185; -.
DR GeneTree; ENSGT00940000158233; -.
DR OMA; YYGPLAC; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF14; NIPA-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 384 AA; 42124 MW; F7F5D13E5722AD43 CRC64;
MDDSQAQQGV SYTDNLIGTL LAISGNLLVS ISLSIQKYSH VKLAGTKEQR TFYQTKTWWS
GFVFICIGEG ANFVSYAFAP IAVVAPLNAV SVLTSSILGF LFLREKSKAK DFAKNHGLTF
LGYVLIIGGT YLFVSFGPNS HEKLQAVNIV RHIVGWPVLL YLLLEIITFC LLLYFYKQRS
ANYLVIILLL VALLGSVTVI TVKAVSGMLL LTLEGSMQLD YPIFTVMFVC MVASVVFQAR
FLSQACNLHD PSLAACINYI FSTCLAVVAG AVFYLEFLNE DVLHICMFVL GSALCFLGVF
LVTKYRKKPK IFEPYVTMDM AKGVPTIHDN GLVVQPDFNG SFSYGSLVNN DGVAPASLPV
NLEHPVVTVR GTDAPHGHPD LKED
//
