ID   A0A3Q2D3L6_CYPVA        Unreviewed;       887 AA.
AC   A0A3Q2D3L6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Protocadherin 20 {ECO:0000313|Ensembl:ENSCVAP00000012912.1};
GN   Name=PCDH20 {ECO:0000313|Ensembl:ENSCVAP00000012912.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000012912.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000012912.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_015226709.1; XM_015371223.1.
DR   AlphaFoldDB; A0A3Q2D3L6; -.
DR   STRING; 28743.ENSCVAP00000012912; -.
DR   Ensembl; ENSCVAT00000030533.1; ENSCVAP00000012912.1; ENSCVAG00000015357.1.
DR   GeneID; 107082503; -.
DR   KEGG; cvg:107082503; -.
DR   CTD; 64881; -.
DR   GeneTree; ENSGT00940000156743; -.
DR   OMA; IEHPAMD; -.
DR   OrthoDB; 4259465at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 7.
DR   Gene3D; 2.60.40.60; Cadherins; 7.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF260; PROTOCADHERIN-20; 1.
DR   Pfam; PF00028; Cadherin; 4.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 7.
DR   SUPFAM; SSF49313; Cadherin-like; 7.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 7.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        826..850
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          34..147
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          156..258
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          259..364
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          371..473
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          474..577
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          578..680
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          684..807
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   887 AA;  98831 MW;  BE2C09AFB19D3FB4 CRC64;
     MLRSRHPSKK GRIWGFYILM LYTSPLCCLA NFSQAKELIY TIKEGLPKGT FIGAIGEDLR
     LDFTVEPPFS FSLTQKKVTE QYVNINNTTG ELYTSAAEID RETLCPYSSD KQGCFFSLDV
     FVLPQQYFQL VKVKLLIEDV NDNRPKFPMD EICMFVPENA QINSRFAVEQ SAVDPDLGIF
     GVQTYWLVND FGVFTLDVEE NDGGELTPFL IITDFLDRET QDEYITDIIA EDGGTPPLLG
     AATLKIAITD VNDNCPKFTE SQINVTLHGN TSKGTHLARL HAFDPDLGTN AEISYAYSER
     VPRDTRSLFH LDKITGGIKL ARKIDSATAT FYKLTVLANG PGCIPAVATV NVHVIKLVTG
     PPDILPRYIA SEKDGVVTLK ESEPAFSPIA FFTIKNMDKT HRVDCYLEGN GPFRLVPYQQ
     LENEYLLETT DTLDYERIQE YELIVVANNT LGMVIKTFLK VQVLDENDNA PVFQQSLVEI
     SIEENNSPNT FLTQLQASDP DSEGRGEVIY ILGGDAPGIF AVDRLTGVLT VATSLDREEK
     EKYRFIVRAV DQGTPRRESL ATVVVTVLDR NDNSPRFINK DFTFFVPENF PGFGEIGVLS
     VTDADAGKNG WVALSILNGS DIFMIDTGRG ALRAKTPLDR EQQGTYQLWI EAADGGVPAL
     SSITMVTVLL LDVNDNPPIV LFPQSNQSYM LVLPSTAPGT SIAEVYAVDK DTGMNAVIAY
     SIIKRKGGEP GSFAIDPQTG NITLMRELSN RGLYSLLVKV TDHGQPEPLY STVMVNFFVN
     ETVSNESYIQ SLLTRDADIE VEEKPWYGGQ MTDGPERYEL FPCRSVLIAL SVVCLGLFFL
     VVILISYICC KRFKKIRHKR SEVEVPLKMK NGSTHDLNRK LRQMSKM
//