ID   A0A3Q2D4W0_CYPVA        Unreviewed;       128 AA.
AC   A0A3Q2D4W0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000256|ARBA:ARBA00040181};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000013402.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000013402.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004434}. Mitochondrion intermembrane
CC       space {ECO:0000256|ARBA:ARBA00004569}.
CC   -!- SIMILARITY: Belongs to the MICU1 family. MICU1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00038333}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q2D4W0; -.
DR   Ensembl; ENSCVAT00000020937.1; ENSCVAP00000013402.1; ENSCVAG00000015889.1.
DR   GeneTree; ENSGT00950000183079; -.
DR   OMA; NTEDYAP; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006851; P:mitochondrial calcium ion transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR039800; MICU1/2/3.
DR   PANTHER; PTHR12294:SF1; CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12294; EF HAND DOMAIN FAMILY A1,A2-RELATED; 1.
DR   Pfam; PF13202; EF-hand_5; 2.
DR   SUPFAM; SSF47473; EF-hand; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00022792};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00022792};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          51..67
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|Pfam:PF13202"
FT   DOMAIN          79..95
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|Pfam:PF13202"
SQ   SEQUENCE   128 AA;  14191 MW;  65429E72CA9DB45C CRC64;
     MILKVAFEKY ASVVEDGEHY MTPRDFVQNY LGLHTQPQHN PKTVELIAGV ADTTKDGLIS
     FQEFLAFESV LCAPDALFIV AFQLFDKNGS GNISFGTYMV SNLLKVVQTL FSSFIFCALQ
     TLSPSTLL
//