ID A0A3Q2D678_CYPVA Unreviewed; 341 AA.
AC A0A3Q2D678;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000013962.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000013962.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC which catalyzes the hydrolysis of ATP coupled with the exchange of
CC Na(+) and K(+) ions across the plasma membrane.
CC {ECO:0000256|RuleBase:RU362099}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC {ECO:0000256|ARBA:ARBA00005876, ECO:0000256|RuleBase:RU362099}.
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DR RefSeq; XP_015257783.1; XM_015402297.1.
DR AlphaFoldDB; A0A3Q2D678; -.
DR STRING; 28743.ENSCVAP00000013962; -.
DR Ensembl; ENSCVAT00000030918.1; ENSCVAP00000013962.1; ENSCVAG00000016519.1.
DR GeneID; 107102854; -.
DR KEGG; cvg:107102854; -.
DR CTD; 64272; -.
DR GeneTree; ENSGT01030000234579; -.
DR OMA; WVPEIYN; -.
DR OrthoDB; 2880589at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 2.60.40.1660; Na, k-atpase alpha subunit; 1.
DR InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR NCBIfam; TIGR01107; Na_K_ATPase_bet; 1.
DR PANTHER; PTHR11523; SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT; 1.
DR PANTHER; PTHR11523:SF47; SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3; 1.
DR Pfam; PF00287; Na_K-ATPase; 1.
DR PROSITE; PS00390; ATPASE_NA_K_BETA_1; 1.
DR PROSITE; PS00391; ATPASE_NA_K_BETA_2; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362099};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362099};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362099};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362099}; Transport {ECO:0000256|RuleBase:RU362099}.
FT TRANSMEM 103..127
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362099"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 39694 MW; FFA8720CEEED0873 CRC64;
MSSTTEVQNQ EPNQEPPKET TNAEQKEEAK EAQGEEKDAA KEEVKVEEKT EEKKEEKKEE
KKEEEKVQKK EEKKDQNKES WKDFIYNPRT GEFLGRTASS WGLIFLFYLI FYGFLAGMFT
LTMWVMLQTL DDNVPRHQDR LANPGLVVRP LGFEISYNRS DPTKYNPYVQ QLHDFLQKYN
DSIQEGNDLC MVGEYTDQDE QPKKKVCQFK RSALRLCSGL PDTSFGYAEG QPCIIVKMNR
VIGLKPQGDP YINCTSKRNT PLQMLYFPPE GRLDKMFFPY YGKNAHPDYV QPLVAVKLLL
TKEDYNVEQT VECKVEGTNL RNNDERDKNM GRVTFRVKVL Q
//
