ID A0A3Q2D8K2_CYPVA Unreviewed; 741 AA.
AC A0A3Q2D8K2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Actin binding LIM protein 1 {ECO:0000313|Ensembl:ENSCVAP00000014928.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000014928.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000014928.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3Q2D8K2; -.
DR Ensembl; ENSCVAT00000022872.1; ENSCVAP00000014928.1; ENSCVAG00000017739.1.
DR GeneTree; ENSGT00950000182850; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF18; ACTIN-BINDING LIM PROTEIN 1; 1.
DR Pfam; PF16182; AbLIM_anchor; 1.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 6.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 24..83
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 84..143
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 151..210
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 673..741
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 266..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..488
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 83650 MW; 68176E89EB6C20ED CRC64;
MVMVKEKVAH TQDTHHHSTE KPLIQCYKCG QPCKGEVLRV QNKHFHLKCF TCKVCGCDLA
QGGFFMKNGD YLCMLDYQRM HGTRCNGCGD FVEGEVVTAL GKTYHPACFV CTICKRPFPA
GDRVTFNGKD CLCQYCAEPM SPGPKDILGS SSCSGCGRDI KNGQALLALD RQWHLGCFKC
KACGKVLTGE YISKDGAPYC EKDYQIHFGV QCEACHQFIT GKVLEAGDKH YHPSCARCSR
CNQMFTEGEE MYLQGSTVWH PGCKNTTRTE ERHRERPTRS SSESICSRPG SSIPGSPGHT
IYAKVDNEIL DYRDLAAIPK VKAIYDIERP DLITYEPMYT TSLDEKEERR ECIGELHSAR
RERSPMPDDK PSRNMSPTPS AEGFYDRRDR ILQRSTSQGS IGSPVYNRHG YTPTLSRSPQ
HFHRPEALTG MQKLCSSLCS NSVGSRNSDS RPTSPFRHHF LPHSQGPDPP SGRSSPLPLR
PDGRPVTPPL SQTPKHFHVP DQGSNIYRKP PIYKLHDLAA VAHQSKSGED IIRSATFPAA
HAPSLDDSSL SEGDCWPHSL AVLGSEGRRK SREEEEEEAL KRKQIQEEHL SKIQSGLGKL
ILKEEMEKEQ IRERHARSLS AQRYEPKMNN CDADPTSPTK TNSLPGYGRN GLHRPQSTDF
TQYNSYGDMC GSGREFQVYP YELLMITSRG RAKLPRDVDR TRLERHLAPE TFFEIFGMEI
QEFDRLPLWK RNDMKKKAKL F
//
