ID   A0A3Q2D9U1_CYPVA        Unreviewed;       410 AA.
AC   A0A3Q2D9U1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Interferon-inducible GTPase 5-like {ECO:0000313|Ensembl:ENSCVAP00000015244.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015244.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000015244.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3Q2D9U1; -.
DR   Ensembl; ENSCVAT00000031443.1; ENSCVAP00000015244.1; ENSCVAG00000000472.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   OMA; KFQPHEY; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          49..229
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   410 AA;  45790 MW;  BDAFF40DECB0C971 CRC64;
     LSVSPRPAVM GENLKADPEV IQAVQNAMGN NTETAEEKLR EYLEFKSKVP LNIAITGGSG
     NGKSSFVNAF RGVDDDDDHA SPTGVKETTM EVKEYPHPNY PNVIISDLPG IGTTKFPASK
     YLKLFGFNKF DLFIIISADR FTENDAKLAK EIDKMKKKFY FVRSKVDVDL QNEQRKKNFS
     EQKTLAEIRE DCVKSLKQHG IESQQVFLVS NHHIHLYDFS LLQETLQRDL PDHRKDALLL
     ASPSIFPGII EKKKKFFRYQ IWFLTALSSV VAAAPLPGLS VGVDLSLLVG AVTHYVFAFA
     LDISSLRRTA ARTGISYDEL IAVLKSQLAA KEITKELITK VILQLPGATK VIVAEEVSKF
     IPLVGIPMSM TFSAATTYNL LKLFLDMLAE DAQRISDRII TDKCRARDML
//