ID   A0A3Q2DB18_CYPVA        Unreviewed;       628 AA.
AC   A0A3Q2DB18;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Actin binding LIM protein family member 3 {ECO:0000313|Ensembl:ENSCVAP00000015699.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015699.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000015699.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A3Q2DB18; -.
DR   STRING; 28743.ENSCVAP00000015699; -.
DR   Ensembl; ENSCVAT00000023857.1; ENSCVAP00000015699.1; ENSCVAG00000018706.1.
DR   GeneTree; ENSGT00950000182850; -.
DR   OMA; FGMTMED; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   CDD; cd09328; LIM2_abLIM; 1.
DR   CDD; cd09329; LIM3_abLIM; 1.
DR   CDD; cd09330; LIM4_abLIM; 1.
DR   Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR   Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR   InterPro; IPR032402; AbLIM_anchor.
DR   InterPro; IPR003128; Villin_headpiece.
DR   InterPro; IPR036886; Villin_headpiece_dom_sf.
DR   InterPro; IPR001781; Znf_LIM.
DR   PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR   PANTHER; PTHR24213:SF0; ACTIN-BINDING LIM PROTEIN 3; 1.
DR   Pfam; PF16182; AbLIM_anchor; 1.
DR   Pfam; PF00412; LIM; 3.
DR   Pfam; PF02209; VHP; 1.
DR   SMART; SM00132; LIM; 3.
DR   SMART; SM00153; VHP; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR   SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR   PROSITE; PS51089; HP; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW   ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT   DOMAIN          65..125
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          135..194
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          560..628
FT                   /note="HP"
FT                   /evidence="ECO:0000259|PROSITE:PS51089"
FT   REGION          364..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..379
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..416
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..467
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  70645 MW;  4CBFB8C8A04F0AD6 CRC64;
     LVKALVGLAQ NAARALSEAP CHCSVFECVS ILFPSVCNCD LARSGFFQKK GEYICTADYQ
     RLYGTRCDRC NSFITGEVVS ALGRAYHPKC FVCSVCSKPF PIGDKVTFSG KDCVCQQCSH
     TLVKSNEPIK IHGPSHCAGC GAEIKQGQSL LALEKQWHVS CFRCQTCNMV LTGEYISKDG
     VPYCEADYHA QYGVKCETCN RYISGRVLEA GGKHYHPTCA RCARCNTMFK EGEEMYLTGC
     EVWHPLCKQA ARAERRLRPR RLSETSISPP GSSIGSPSRV ICARVQNEIF DYKDLAALPK
     VKAIYEVQQP DLISSSYQPY HRYTSDERLD TFSYGESLGT LSPYSQDYDN PDAKQHRFSI
     PGYIDSPTYS RQGMSPITPR SPQHFGYPGS ESGRSSPYYG QDGRSSTPTT NQPPKHFHVP
     ATEDPNIYRK PPIYKRTATK SRTSEDILRS SSLSTYSPEP YMQSESDYYP YTSSPRAYWA
     PRRRFSTGGD EESWSQGLQR IGSGIGRMIL KEEMKARSGS YDNDPWGSAR NSRCGSKETL
     NTTGYGTTPQ SADCYQYQYD AGSEIYPYES LIVTTRGRNK LPKDVDRARL ERHLSPEEFV
     QVFGMSVEDF DRLALWKRNE LKKQARLF
//