ID A0A3Q2DB44_CYPVA Unreviewed; 1450 AA.
AC A0A3Q2DB44;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSCVAP00000015983.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015983.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000015983.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR STRING; 28743.ENSCVAP00000015983; -.
DR Ensembl; ENSCVAT00000024226.1; ENSCVAP00000015983.1; ENSCVAG00000018862.1.
DR GeneTree; ENSGT00940000156524; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR045914; Zn532-like.
DR InterPro; IPR041697; Znf-C2H2_11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47222; ZINC FINGER PROTEIN 532-RELATED; 1.
DR PANTHER; PTHR47222:SF2; ZINC FINGER PROTEIN 687; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF16622; zf-C2H2_11; 1.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 673..691
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 866..894
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1018..1045
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1049..1077
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1162..1189
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1188..1216
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1322..1349
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1351..1379
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1414..1449
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 23..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1070..1157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1243..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1375..1407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..252
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1140
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1278..1295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1450 AA; 153624 MW; B888292BE802E5D5 CRC64;
MGDMKTPDFD DLLAAFDIPD IDAKEAIQSA PDDAEGPHGA AGAPLGKQEG VVGVGSSLRP
PSPADSQADT SIVSVIVKNK VRHEAVDGGD GDSDQHPIDM MAGADAGPRL GACAESEALN
HNGFGASSVS TPLPLGQNQS NGSPWSVNTP KASAEAAGVS TAKSHKQGGN IFNRLKPLVA
QGSGDPVGRA RKMQLLQQQH QQQQDTGEER ADAVKASLPS SSSVSAGSSP LAAGLSLPFF
PPPKPLLSAP PSAPSSQPFN GAPKGGAGGF QHQVEEEDSD PDLGSPLVIQ ENPDSPASAQ
MSRRYKSDSV SSQPASSTAS QPKPGNTPSA PVPQPSSAEA PQVEERHPEH VIEERDSPES
PEPEMPNSAA QVPGKTCSSP AVASTPPPSE LRVPKEEEVE MEVGNGIDRV VDGKGEKGEN
MRTSEENMEV DDGKSKPSST DGGESAPSAV PAPPGAPSRP LKVRIKTIKT STGGITRTVT
RVASKGGAGG KGLEPKAQTG EHKLLVNKTQ KPVLTTTSSQ KVSALNSLPV STLAASSVML
AAATKVQNKM ASTDKAKVSA TAVSITKSAA LPATPAVASS PKFSVAASGI SVRTATNKSA
NGGGTAISGN TLQANKPASI VNNTGAVISR SQSSLVEAFN KILNSKNLLP SYKPDLSAPP
PPEWGLPLPA TGYRCLECGD AFALERSLAR HYDRRSLRIE VTCNHCAKRL AFFNKCSLLL
HAREHKERGL VMQCSHLVMR PVTVEQMIGQ QDIMPIGGKW NRESLTFHPK HLFFSPIFTD
HHPYFLSVFH RLAEPGLLTS SSSPPVSSPS ATSGGPAATA SSSPMKDTSS PAAAAPPRPV
RRAPQGPQAL MPLPCKKAEG LQYNNFKCPE CQTQFSSKAE LVTHFQQIRG APSSTCSQCS
PPMMLPNSCA VSAHQRIHKH KAPYVCPECG GTARQTSFQT HLDEACLHFA RRIGYRCSSC
QVVFGGLNSI KSHIQTAHCE VFHKCPSCPM AFKSSPSAQN HISTQHPTLT GGQAKMIYKC
VMCDTVFTQK PLLYMHFDTH LAKQKVHVFK CPDCTKLYAQ KGSMMEHIKT AHRGPAAKQE
SQPDTSNPAS APTNSSSPSG LKLKPSAKPD TSDGEDWGRE QEEEEEEEED DDDEGDEDYE
APGGQSGGGT GGSGHSTAVN EWTCPQCQTT FTDNDDYQSH VKMEHGKFPC RICGGTFSTS
SSLRRHERVI HEGNKRVFHC QFCTEGKRTF GSRFLLDKHI RLHHRPTDGQ GPPLTRKRAA
TGGEGAGSSS EHDGEVGPPA GRQADEEEGA TEEGGGPAKR TRASMASTSS APSELEEEDS
IFRCVPCGFS TEDGAEFQRH IPQHRGDTAA FQCLQCGVCF ASAGSLSRHR FITHRVRDTQ
NDTERGTPRA PGSPSTSPGD ASPLAHLEDG DGNLGCRVCG RRFDKATDLN THFRTHGMAF
LTAHKTDKPQ
//
